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(2,6-diethyl-4-methylphenyl)malonic acid dimethyl ester, also known as (2,6-diethyl-4-methylphenyl) diethylmalonate, is an organic compound with the molecular formula C16H24O4. It is an ester derivative of malonic acid and is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. This chemical is a colorless to pale yellow liquid with a slightly fruity odor. It is known for its high boiling point and is often used as a solvent or a reagent in various chemical reactions. Additionally, it has been investigated for its potential biological activity and therapeutic properties, making it a subject of interest in medicinal chemistry research.

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  • 243973-72-0 Structure
  • Basic information

    1. Product Name: (2,6-diethyl-4-methylphenyl)malonic acid dimethyl ester
    2. Synonyms: (2,6-diethyl-4-methylphenyl)malonic acid dimethyl ester
    3. CAS NO:243973-72-0
    4. Molecular Formula:
    5. Molecular Weight: 278.348
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 243973-72-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (2,6-diethyl-4-methylphenyl)malonic acid dimethyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: (2,6-diethyl-4-methylphenyl)malonic acid dimethyl ester(243973-72-0)
    11. EPA Substance Registry System: (2,6-diethyl-4-methylphenyl)malonic acid dimethyl ester(243973-72-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 243973-72-0(Hazardous Substances Data)

243973-72-0 Usage

Uses

Used in Pharmaceutical Industry:
(2,6-diethyl-4-methylphenyl)malonic acid dimethyl ester is used as an intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into complex organic compounds, contributing to the development of new drugs and therapies.
Used in Organic Synthesis:
(2,6-diethyl-4-methylphenyl)malonic acid dimethyl ester is used as a reagent in organic synthesis for its versatility in forming esters and other derivatives, facilitating the creation of a wide range of organic compounds.
Used as a Solvent:
(2,6-diethyl-4-methylphenyl)malonic acid dimethyl ester is used as a solvent in various chemical reactions due to its high boiling point and ability to dissolve a variety of substances, making it suitable for use in industrial processes.
Used in Medicinal Chemistry Research:
(2,6-diethyl-4-methylphenyl)malonic acid dimethyl ester is used in medicinal chemistry research for its potential biological activity and therapeutic properties, as scientists explore its applications in the development of new treatments and medicines.

Check Digit Verification of cas no

The CAS Registry Mumber 243973-72-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,3,9,7 and 3 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 243973-72:
(8*2)+(7*4)+(6*3)+(5*9)+(4*7)+(3*3)+(2*7)+(1*2)=160
160 % 10 = 0
So 243973-72-0 is a valid CAS Registry Number.

243973-72-0Relevant articles and documents

Preparation method and application of 2-6 -diethyl -4 methylphenylpropionic acid diester

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Paragraph 0050-0054; 0060-0065, (2021/09/01)

The invention belongs to the technical field of synthesis of an oxazoline intermediate, and particularly provides a preparation method of 2-6 -diethyl -4 methylphenylpropionic acid diester, in particular to an inorganic acid with 2, 6 -diethyl -4 methylph

Preparation method of intermediate compound 2, 6 - diethyl -4 - methylbenzene malonate (by machine translation)

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Paragraph 0036; 0049; 0051; 0060; 0063, (2019/10/01)

The method has the advantages of mild reaction conditions, wide raw material source and short synthetic route, and CuI and L - proline are used as a catalyst system, and 2, 6 -diethyl -4 -4 - methyliodobenzene and malonic acid diester are subjected to cou

Method for preparing pinoxaden key intermediate

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Paragraph 0026; 0027; 0029; 0034; 0035; 0043; 0044; 0055, (2019/01/16)

The invention discloses a method for preparing a pinoxaden key intermediate. The method includes step 1 of utilizing 2,6-diethyl-4-methylbromobenzene as a raw material and first undergoing reaction with a magnesium strip in a tetrahydrofuran solvent to pr

Preparation method and intermediate of pinoxaden

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, (2018/07/30)

The invention provides a preparation method and an intermediate of pinoxaden. The preparation method includes: using 2-methylacrolein as a raw material; subjecting the raw material to cyclization andaromatization to obtain herbicide-pinoxaden. Compared with the prior art, the preparation method has the distinguishing features and the advantages that a completely different preparation strategy isadopted; a completely different nonaromatic compound is used as the raw material which is safe and easy to obtain; the preparation method is few in three wastes, low in cost and conducive to industrial production.

Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden

Muehlebach, Michel,Boeger, Manfred,Cederbaum, Fredrik,Cornes, Derek,Friedmann, Adrian A.,Glock, Jutta,Niderman, Thierry,Stoller, Andre,Wagner, Trixie

experimental part, p. 4241 - 4256 (2009/10/02)

Derivatives of the new class of 3-hydroxy-4-phenyl-5-oxo-pyrazolines were optimized towards both herbicidal activity on key annual grass weed species and selectivity in small grain cereal crops. The generic structure can be separated into three parts for the analysis of the structure-activity relationships, namely the aryl, the dione with its prodrug forms and the hydrazine moiety. Each area appears to play distinct and different roles in overall expression of biological performance which is further beneficially influenced by adjuvant response and safener action. Pinoxaden 6, a novel graminicide for use in wheat and barley incorporating a [1,4,5]oxadiazepane ring, eventually emerged as a development candidate from the discovery and optimization process.

p-Tolyl-heterocycles as herbicides

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Page 44, (2008/06/13)

Aryl-substituted (hetero)cyclic keto-enols (I) are new. Also new are selective herbicidal agents containing these keto-enols and a safener. The enol ethers are prepared from partly new halo-substituted toluene intermediates. The aryl-substituted (hetero)c

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