31404-08-7

Basic information

• Product Name: 2-(4-METHOXY-PHENYL)-THIAZOLIDINE
• Synonyms: TIMTEC-BB SBB010939;2-(4-METHOXYPHENYL)-1,3-THIAZOLANE;2-(4-METHOXY-PHENYL)-THIAZOLIDINE;IFLAB-BB F0804-1064;2-(4-Methoxyphenyl)-1,3-thiazolidine
• CAS NO: 31404-08-7
• Molecular Formula: C₁₀H₁₃NOS
• Molecular Weight: 195.28
• Mol File: 31404-08-7.mol

Chemical Properties

• Melting Point: 100-102
• Boiling Point: 341.8 °C at 760 mmHg
• Flash Point: 160.5 °C
• Appearance: /
• Density: 1.132 g/cm³
• Vapor Pressure: 7.84E-05mmHg at 25°C
• Refractive Index: 1.568
• CAS DataBase Reference: 2-(4-METHOXY-PHENYL)-THIAZOLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-METHOXY-PHENYL)-THIAZOLIDINE(31404-08-7)
• EPA Substance Registry System: 2-(4-METHOXY-PHENYL)-THIAZOLIDINE(31404-08-7)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 31404-08-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
2-(4-Methoxy-phenyl)-Thiazolidine is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows it to be a valuable building block in the development of new drugs, although further research is needed to fully understand its potential in this field.
Used in Organic Chemistry:
2-(4-Methoxy-phenyl)-Thiazolidine is used as a building block in organic chemistry, providing a foundation for the creation of more complex molecules. Its thiazolidine backbone and 4-methoxyphenyl group offer opportunities for further chemical reactions and modifications, making it a versatile compound in the field of organic synthesis.
Further studies are required to better understand the properties and potential applications of 2-(4-Methoxy-phenyl)-Thiazolidine, as its current uses are not widely documented in public databases. 2-(4-METHOXY-PHENYL)-THIAZOLIDINE holds promise for future advancements in pharmaceuticals and organic chemistry, pending further exploration and research.

InChI:InChI=1/C10H13NOS/c1-12-9-4-2-8(3-5-9)10-11-6-7-13-10/h2-5,10-11H,6-7H2,1H3

Upstream product

• 156-57-0 2-mercaptoethylamine hydrochloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 60-23-1 Cysteamine 

Downstream Products

• 67189-40-6 2-(4-methoxy-phenyl)-3-methyl-thiazolidine 
• 112562-31-9 2-(4-Methoxy-phenyl)-thiazolidine-3-carbothioic acid methylamide 

Relevant articles and documents

First example of the ring-opening transformation of thiazolidines to iminothiols on gold surface

A new way to construction of the self-assembling monolayers on gold surfaces based on ring opening reactions of thiazolidines to iminothiols followed by Au-S bond formation has been proposed.

NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR

Provided are a novel compound having skin-whitening, anti-oxidizing and PPAR activities and a medical use thereof, and the compound has skin-whitening activities for the suppression of tyrosinase, and accordingly, is useful for use in skin-whitening pharmaceutical composition or cosmetic products; has anti-oxidant activities, and accordingly, is useful for the prevention and treatment of skin-aging; and has PPAR activities, and in particular, PPARα and PPARγ activities, and accordingly, is useful for use in pharmaceutical compositions or health foods which are effective for the prevention and treatment of obesity, metabolic disease, or cardiovascular disease.

Evolution of thiazolidine-based blockers of human Kv1.5 for the treatment of atrial arrhythmias

Blockade of the Kv1.5 ion channel is a potentially atrial-selective avenue for the treatment of atrial fibrillation and atrial flutter. The development and biological evaluation of a series of thiazolidine-based blockers of Kv1.5 is described.

NOVEL METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASES

Methods of inhibiting the cytokine or biological activity of Macrophage Migration Inhibitory Factor (MIF) comprising contacting MIF with a compound of formula (I) are provided. The invention also relates to methods of treating diseases or conditions where MIF cytokine or biological activity is implicated comprising administration of compounds of formula (I), either alone or as a part of combination therapy. Novel compounds of formula (I) are also provided for.

Comparative radioprotective activity of various pentagonal compounds with two heteroatomes

Various heterocyclic compounds with two heteroatomes were synthesized and their potential radioprotective activity was tested. This study shows the interest of phenylthiazolidines derivatives in chemical radioprotection.