314046-82-7Relevant articles and documents
Enantioselective N-Acylation of Biginelli Dihydropyrimidines by Oxidative NHC Catalysis
Brandolese, Arianna,Ragno, Daniele,Leonardi, Costanza,Di Carmine, Graziano,Bortolini, Olga,De Risi, Carmela,Massi, Alessandro
, p. 2439 - 2447 (2020/04/30)
The oxidative N-acylation reaction of 3,4-dihydropyrimidin-2-(1H)-ones (DHPMs) with enals and N-heterocyclic carbene (NHC) catalysts is described. The reaction proceeds in the presence of quinone oxidant without additional acyl transfer agents and in the
Pharmacologically relevant bifunctional compounds containing chloroquinoline and dihydropyrimidone moieties: Syntheses and crystal structures of a target molecule and selected intermediates
Watermeyer, Nicholas D.,Chibale, Kelly,Caira, Mino R.
experimental part, p. 753 - 760 (2010/06/19)
We report the regioselective synthesis and X-ray structure of the pharmacologically relevant 3-[2-(7-chloro-quinolin-4-ylamino)-ethylcarbamoyl]-4- (4-methoxy-phenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5- carboxylic acid methyl ester (3) (tri