31413-80-6Relevant academic research and scientific papers
Oxidant-switchable selective synthesis of 2-aminobenzimidazoles via c-h amination/acetoxylation of guanidines
Chi, Yue,Zhang, Wen-Xiong,Xi, Zhenfeng
, p. 6274 - 6277 (2014)
The iodine(III) compound promoted C-H amination and tandem C-H amination/acetoxylation of guanidines are achieved for the first time to provide efficiently 2-aminobenzimidazoles and acetoxyl-substituted 2-aminobenzimidazoles, respectively. The amount and
Synthesis of a tetracyclic aminobenzimidazole derivative via tandem cyclization of triphenylguanidine
Akamatsu, Yuki,Kamino, Shinichiro,Sawada, Daisuke
, p. 815 - 819 (2019/08/01)
We developed a new reaction for the one-pot synthesis of a fused cyclic compound from triphenylguanidine, which was thought to be tandem cyclization, with a moderate yield. In this reaction, conditions such as the metal reagent, oxidant, solvent, and liga
Eco-friendly strategy: design and synthesis of biologically potent benzimidazole-amine hybrids via visible-light generated oxidative C-H arylamylation of analenic amidines
Siddiqui,Ibad, Farah,Ibad, Afshan,Abdul Waseem, Malik,Watal, Geeta
, p. 5 - 10 (2015/12/23)
An operationally simple visible light mediated intramolecular cyclization of benzimidazole to 2-amino benzimidazole hybrid. The disclosed procedure is rapid and the convenient synthesis of benzimidazole-amine hybrids from easily available substituted cycl
Copper-catalyzed synthesis of 2-aminobenzimidazoles from carbonimidoyl dichlorides and amines
Yu, Hui,Liu, Qiong,Li, Yuzhe,Ni, Chongzhi
, p. 5253 - 5256 (2012/10/30)
A new protocol for the synthesis of a variety of 2-aminobenzimidazole derivatives has been developed. O-haloaryl carbonimidoyl dichloride reacted with anilines to generate an o-haloaryl guanidine intermediate, which underwent copper catalyzed ring closure to afford 2-aminobenzimidazole derivative in moderate yields.
A protocol to 2-aminobenzimidazoles via copper-catalyzed cascade addition and cyclization of o-haloanilines and carbodiimides
Wang, Fei,Cai, Shangjun,Liao, Qian,Xi, Chanjuan
experimental part, p. 3174 - 3180 (2011/06/24)
An efficient strategy for the synthesis of a variety of 2-animobenzimidazole derivatives has been developed. The reaction proceeded from o-haloanilines and carbodiimides via copper(I)-catalyzed domino reaction in the presence of tert-butoxide to afford the corresponding 2-animobenzimidazole derivatives in good to excellent yields. o-Haloanilines could be o-iodoaniline, o-bromoaniline, and o-chloroaniline derivatives. Carbodiimides could be symmetrical and unsymmetrical substrates with aryl or alkyl substituents. The reaction exhibited a good regioselectivity when unsymmetrical carbodiimides were employed.
Regiospecific synthesis of 1, 2-disubstituted (hetero)aryl fused imidazoles with tunable fluorescent emission
Zhao, Dongbing,Hu, Junyi,Wu, Ningjie,Huang, Xiaolei,Qin, Xurong,Lan, Jingbo,You, Jingsong
supporting information; experimental part, p. 6516 - 6519 (2012/02/02)
A palladium-catalyzed two or fourfold amination was established that allows regiospecific synthesis of a diversity-oriented library of 1, 2 disubstituted (hetero)aryl fused imidazoles, and provides an exceptional tool for the discovery of fluorescent scaf
Synthesis of benzoxazole and benzimidazole derivatives via ligand-free copper(I)-Catalyzed cross-coupling reaction of o-halophenols or o-haloanilines with carbodiimides
Shen, Guodong,Bao, Weiliang
supporting information; experimental part, p. 981 - 986 (2010/06/15)
A novel and efficient synthesis of benzoxazole and benzimidazole derivatives via a ligandfree, copper(I)-catalyzed, one-pot cascade process has been developed. A variety of carbodiimides coupled with o-halophenols or o-haloanilines to give the products in moderate to excellent yields under the mild conditions.
