31427-08-4

Usage

Uses

Used in Pharmaceutical Industry:
4-Hydroxy-2-methoxyphenyl β-D-glucopyranoside is used as a skin-whitening agent for its ability to inhibit the production of melanin, the pigment responsible for skin color. It is commonly used in the formulation of various skincare products, including creams, lotions, and serums, to help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone.
Used in Cosmetic Industry:
In the cosmetic industry, 4-Hydroxy-2-methoxyphenyl β-D-glucopyranoside is utilized as an active ingredient in various products aimed at improving skin complexion and reducing the signs of aging. Its skin-whitening properties make it a popular choice for anti-aging and brightening products, as well as those targeting acne scars and other skin discolorations.
Used in Traditional Medicine:
4-Hydroxy-2-methoxyphenyl β-D-glucopyranoside has been used in traditional medicine for its anti-inflammatory and antimicrobial properties. It is believed to help soothe and heal skin irritations, rashes, and minor wounds, making it a valuable component in topical remedies and ointments.
Used in Food Industry:
In the food industry, 4-Hydroxy-2-methoxyphenyl β-D-glucopyranoside may be used as a natural preservative due to its antimicrobial properties. It can help extend the shelf life of certain food products by inhibiting the growth of bacteria and other microorganisms, ensuring freshness and safety for consumers.
Used in Research and Development:
4-Hydroxy-2-methoxyphenyl β-D-glucopyranoside is also used in research and development for its potential applications in various fields, including pharmaceuticals, cosmetics, and food science. Scientists are continually exploring its properties and potential benefits to develop new and innovative products and applications.

Upstream product

• 824-46-4 methoxyhydroquinone 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 6195-80-8 2,4-bis(benzyloxy)phenol 
• 74808-10-9 O-(2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl)trichloroacetimidate 
• 251921-28-5 2,4-dihydroxyphenyl-tetra-O-acetyl-β-D-glucopyranoside 
• 251921-27-4 1-O-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)-2,4-dibenzyloxybenzene 

Downstream Products

• 824-46-4 methoxyhydroquinone 

Relevant academic research and scientific papers

Chemical synthesis and tyrosinase-inhibitory activity of isotachioside and its related glycosides

Isotachioside (1) and its related natural product 2 are isolated from Isotachis japonica and Protea neriifolia, respectively, and are categorized as analogs of arbutin (3), a tyrosinase inhibitor for practical use. Both of the natural products and several derivatives such as glucoside 4, xyloside 5, cellobioside 6, and maltoside 7 were synthesized via Schmidt glycosylation as a key step, and their tyrosinase inhibitory activity was evaluated. The half maximal inhibitory concentration (IC50) of 1–3 could not be determined even when the concentration was increased to 1000 μM. Contrastingly, glycosides 4–7, missing methyl and benzoyl groups, acted as tyrosinase inhibitors with IC50s of 417 μM, 852 μM, 623 μM, and 657 μM, respectively. Among these novel inhibitors, derivative 4 was the most potent, indicating that the structural combination of resorcinol and glucose was significant for inducing the inhibitory effect.

Activity-Guided Identification of in Vitro Antioxidants in Beer

In order to locate the key antioxidants contributing to oxidative stability of beer, activity-guided fractionation in combination with the oxygen radical absorbance capacity (ORAC) assay, hydrogen peroxide scavenging (HPS) assay, and linoleic acid (LA) assay was applied to a pilsner-type beer. LC-MS and 1D/2D NMR experiments led to the identification of a total of 31 antioxidants, among which 3-methoxy-4-hydroxyphenyl-β-d-glucopyranoside (tachioside), 4-(2-formylpyrrol-1-yl)butyric acid, 4-[2-formyl-5-(hydroxymethyl)pyrrol-1-yl]butyric acid, n-multifidol-3-O-β-d-glucoside, quercetin-3-O-(6″-malonyl)-glucoside, 4-feruloylquinic acid, syringaresinol, saponarin, and hordatines A-C have been isolated from beer for the first time. On a molar comparison, the hordatines A-C, saponarin, and quercetin-3-O-β-d-(6″-malonyl)glucoside were evaluated with the highest antioxidant activities of all identified beer constituents, reaching values of 10-17.5 (ORAC), 2.0-4.1 (HPS), and 1.1-6.1 μmol TE/μmol (LA) for hordatines A-C.