31438-18-3

Upstream product

• 106-49-0 p-toluidine 
• 89-60-1 1-chloro-4-methyl-2-nitro-benzene 
• 87995-57-1 N,N-Bis(4-methylphenyl)benzamid 
• 624-31-7 4-tolyl iodide 
• 89-62-3 4-methyl-2-nitroaniline 
• 6947-35-9 nitroso-di-p-tolyl-amine 

Downstream Products

• 219756-64-6 4-methyl-N¹-p-tolyl-o-phenylenediamine 
• 109259-04-3 (4-methyl-2-nitro-phenyl)-nitroso-p-tolyl-amine 
• 65712-02-9 bis(4-methyl-2-nitrophenyl)amine 
• 96048-82-7 5-methyl-2-phenyl-1-(p-tolyl)-1H-benzo[d]imidazole 

Relevant academic research and scientific papers

Ligand-Enabled Gold-Catalyzed C(sp2)-N Cross-Coupling Reactions of Aryl Iodides with Amines

The first example of ancillary (P,N)-ligand-enabled gold-catalyzed C-N cross-coupling reactions of aryl iodides with amines is reported. The high generality of the reaction in de novo synthesis, late-stage modifications, and cascade processes to access functionalized indolinones and carbazoles underscores the synthetic potential of the presented strategy. Monitoring the reaction with ESI-HRMS and NMR provided strong evidence for the in situ formation of putative high valent Au(III) intermediates.

Synthetic derivatives of mauveine

Oxidation of phenosafranin and an excess of aniline gave a novel hydroxylated derivative of pseudo-mauveine. N-Methyl-p-toluidine and bis(4-methylphenyl)amine are efficient building blocks for making mauveine-related chromophores. Their oxidation with Ks