314741-39-4

Basic information

• Product Name: (S)-4-N-Boc-piperazine-2-carboxylic acid methyl ester
• Synonyms: (S)-1-N-Boc-piperazine-3-carboxylic acid methyl ester;(S)-N4-BOC-PIPERAZINE-2-CARBOXYLIC ACID METHYL ESTER;(S)-4-Boc-Piperazine-2-carboxylic acid methyl ester;Methyl (S)-4-Boc-piperazine-2-carboxylate;(S)-4-N-Boc-piperazine-2-carboxylic acid methyl ester;REF DUPL: (S)-4-N-Boc-piperazine-2-carboxylic acid methyl ester;(S)-4-Boc-piperazine-2-carboxylic a;1-tert-butyl 3-methyl (3R)-piperazine-1,3-dicarboxylate
• CAS NO: 314741-39-4
• Molecular Formula: C11H20N2O4
• Molecular Weight: 244.289
• Product Categories: Piperaizine
• Mol File: 314741-39-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 321.3 °C at 760 mmHg
• Flash Point: 148.1 °C
• Appearance: /
• Density: 1.118 g/cm³
• Vapor Pressure: 0.000301mmHg at 25°C
• Refractive Index: 1.471
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 6.45±0.40(Predicted)
• CAS DataBase Reference: (S)-4-N-Boc-piperazine-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-N-Boc-piperazine-2-carboxylic acid methyl ester(314741-39-4)
• EPA Substance Registry System: (S)-4-N-Boc-piperazine-2-carboxylic acid methyl ester(314741-39-4)

Safety Data

• Hazardous Substances Data: 314741-39-4(Hazardous Substances Data)

Usage

General Description

(S)-4-N-Boc-piperazine-2-carboxylic acid methyl ester is a chemical compound that belongs to the class of piperazine derivatives. It is a methyl ester of 4-N-Boc-piperazine-2-carboxylic acid, and its structure consists of a piperazine ring with a Boc (tert-butyloxycarbonyl) protecting group at the nitrogen atom and a carboxylic acid group at the adjacent carbon atom. (S)-4-N-Boc-piperazine-2-carboxylic acid methyl ester is commonly used in the synthesis of pharmaceuticals and other organic compounds due to its versatile reactivity and potential pharmacological activities. It is also utilized as a building block in the preparation of various bioactive molecules. Additionally, it is important to handle and store this compound with proper safety precautions and in accordance with chemical handling guidelines.

InChI:InChI=1/C11H20N2O4/c1-11(2,3)17-10(15)13-6-5-12-8(7-13)9(14)16-4/h8,12H,5-7H2,1-4H3/t8-/m1/s1

Upstream product

• 314741-38-3 1-benzyl 4-(tert-butyl) 2-methyl (2S)-piperazine-1,2,4-tricarboxylate 

Downstream Products

• 314741-40-7 (3S)-3-(hydroxymethyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester 

Relevant articles and documents

SATURATED BICYCLIC HETEROCYCLIC DERIVATIVES AS SMO ANTAGONISTS

The present invention relates to compounds of formula I: and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of the Sonic Hedgehog pathway, in particular Smoantagonists. Thus the compounds of this invention are useful for the treatment of diseases associated with abnormal hedgehog pathway activation, including cancer, for example basal cell carcinoma, medulloblastoma, prostate, pancreatic, breast, colon, bone and small cell lung cancers, and cancers of the upper GI tract.

Compounds and methods for the treatment of neoplastic disease

A method of modulating the activity of a aberrant cell topoisomerase enzyme involving contacting the enzyme with a compound that inhibits enzyme-mediated cleavage of a polynucleotide substrate with which the enzyme is in complex. Pharmaceutical compositions containing such compounds may be used to treat neoplasias or to inhibit the growth of certain cancer cells. Screening methods can be employed to identify other compounds for these uses.