31479-31-9Relevant academic research and scientific papers
Regioselective Synthesis of Thieno[3,2-b]quinolones by Acylation/Two-Fold Buchwald–Hartwig Reactions
Janke, Julia,Ehlers, Peter,Villinger, Alexander,Langer, Peter
, p. 7255 - 7263 (2019)
A variety of thienoquinolones were synthesized from readily accessible thiophene derivatives by regioselective acylations and subsequent two-fold Buchwald–Hartwig–amination. This cyclization allows a convenient synthesis of biologically and pharmaceutically important thienoquinolones. Several thienoquinolones were synthesized in good to very good yields. The optical properties of the products were studied in detail.
