315183-07-4Relevant academic research and scientific papers
Synthesis, molecular modeling and evaluation of novel N′-2-(4- benzylpiperidin-/piperazin-1-yl)acylhydrazone derivatives as dual inhibitors for cholinesterases and Aβ aggregation
Oezturan Oezer, Eda,Unsal Tan, Oya,Ozadali, Keriman,Kuecuekkilinc, Tuba,Balkan, Ayla,Ucar, Guelberk
, p. 440 - 443 (2013/02/23)
To develop new drugs for treatment of Alzheimer's disease, a group of N′-2-(4-Benzylpiperidin-/piperazin-1-yl)acylhydrazones was designed, synthesized and tested for their ability to inhibit acetylcholinesterase, butyrylcholinesterase and aggregation of a
