315668-34-9

Upstream product

• 315668-28-1 N,N-diisopropyl-2-hydroxy-5-(methoxymethoxy)-3-(trimethylsilyl)benzamide 
• 315668-25-8 4-(methoxymethoxy)-2-(trimethylsilyl)phenyl N,N-diisopropyl carbamate 
• 315668-02-1 4-(methoxymethoxy)phenyl N,N-diisopropylcarbamate 
• 315668-01-0 4-hydroxyphenyl N,N-diisopropylcarbamate 
• 123-31-9 hydroquinone 
• 315668-33-8 2-(diisopropylcarbamoyl)-4-(methoxymethoxy)-6-(trimethylsilyl)phenyl propionate 

Relevant academic research and scientific papers

Atropisomeric benzamides and naphthamides as chiral auxiliaries

Atropisomeric compounds whose chirality resides in a rotationally restricted aryl-CONR2 bond may be employed as chiral auxiliaries. The electron-withdrawing amide group causes problems in the diastereoselective functionalisation of enolates derived from atropisomeric phenyl esters, but a strategy based on atroposelective nucleophilic addition to a chiral aldehyde followed by stereospecific [3,3] sigmatropic rearrangement allows atropisomeric naphthamides to be used as auxiliaries. The auxiliaries are resolved by dynamic resolution during aminal formation using a proline-derived diamine. The Royal Society of Chemistry 2000.