315668-39-4

Upstream product

• 123-31-9 hydroquinone 
• 19009-39-3 N,N-diisopropylcarbamoyl chloride 
• 315668-01-0 4-hydroxyphenyl N,N-diisopropylcarbamate 

Downstream Products

• 315668-40-7 N,N,N',N'-tetraisopropyl 3,6-bis(trimethylsilyl)benzene-1,4-diyl dicarbamate 

Relevant academic research and scientific papers

Atropisomeric benzamides and naphthamides as chiral auxiliaries

Atropisomeric compounds whose chirality resides in a rotationally restricted aryl-CONR2 bond may be employed as chiral auxiliaries. The electron-withdrawing amide group causes problems in the diastereoselective functionalisation of enolates derived from atropisomeric phenyl esters, but a strategy based on atroposelective nucleophilic addition to a chiral aldehyde followed by stereospecific [3,3] sigmatropic rearrangement allows atropisomeric naphthamides to be used as auxiliaries. The auxiliaries are resolved by dynamic resolution during aminal formation using a proline-derived diamine. The Royal Society of Chemistry 2000.