3158-63-2

Usage

Uses

Used in Dietary Supplements:
Dihydro-1,3-dimethyl-2-thioxo-4,6(1H,5H)-pyrimidinedione is used as a dietary supplement for its vitamin thiamine (Vitamin B1) content, which is essential for maintaining normal metabolic functions and overall health.
Used in Neurodegenerative Disease Treatment:
In the medical industry, Dihydro-1,3-dimethyl-2-thioxo-4,6(1H,5H)-pyrimidinedione is used as a neuroprotective agent in the treatment of neurodegenerative diseases. Its antioxidant properties contribute to its effectiveness in protecting neurons and slowing down the progression of these diseases.
Used in Pharmaceutical Industry:
Dihydro-1,3-dimethyl-2-thioxo-4,6(1H,5H)-pyrimidinedione is used as an intermediate in the synthesis of other compounds in the pharmaceutical industry. Its unique chemical structure allows it to be a valuable building block for the development of new drugs and therapeutic agents.

Upstream product

• 534-13-4 N,N-dimethylthiourea 
• 105-53-3 diethyl malonate 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 

Downstream Products

• 37042-06-1 1,3-dimethyl-5-(4-oxo-2-phenyl-4H-chromen-3-ylmethylene)-2-thioxo-dihydro-pyrimidine-4,6-dione 
• 78943-22-3 5-[(E)-3-(4-Dimethylamino-phenyl)-allylidene]-1,3-dimethyl-2-thioxo-dihydro-pyrimidine-4,6-dione 
• 331950-83-5 5-(2,4-dichloro-benzylidene)-1,3-dimethyl-2-thioxo-dihydro-pyrimidine-4,6-dione 
• 368889-19-4 5-(3,4-dimethoxy-benzylidene)-1,3-dimethyl-2-thioxo-dihydro-pyrimidine-4,6-dione 
• 112328-80-0 5-(4-methoxy-benzylidene)-1,3-dimethyl-2-thioxo-dihydro-pyrimidine-4,6-dione 

Relevant academic research and scientific papers

COMPOUND, ORGANIC PHOTOELECTRONIC DEVICE AND IMAGE SENSOR

A compound is represented by Chemical Formula 1: [in-line-formulae]X1-T-X2 [/in-line-formulae]wherein T is a substituted or unsubstituted fused thiophene moiety, and each of X1 and X2 are independently an organic group including an alkenylene group and an electron withdrawing group.

An efficient one-pot protocol for regioselective synthesis of 3-aryl-6,8-dialkyl-7-thioxo-7,8-dihydropyrimido[4,5-c ] pyridazine-5(6 H)-ones

A series of 3-aryl-6,8-dialkyl-7-thioxo-7,8-dihydropyrimido[4,5-c] pyridazine-5(6H)-one derivatives have been regioselectively synthesized via the one-pot three-component reaction of 1,3-dimethylthiobarbituric acid and 1,3-diethylthiobarbituric acid with various arylglyoxals in the presence of hydrazinium dihydrochloride in warm ethanol. These new substituted pyrimidopyridazines may be potential monoamine oxidase inhibitors.

One or two step acid mediated cyclocondensation process for the preparation of 5-carbethoxy-2-thiouracils from diethyl ethoxymethylenemalonate and thioureas

An acid mediated synthesis of 5-carbethoxy-2-thiouracils via an one step cyclocondensation of diethyl ethoxymethylenemalonate and thioureas or the under milder reaction conditions, also obtained, thioureidomethylenemalonates, is described here.

Chemical modification of plant alkaloids. 2. Reaction of cotarnine with barbituric acid derivatives and structure of 5-dihydrocotarnylbarbituric acids

The reaction of barbituric acid and its N-substituted derivatives and 2-thio analogs with cotarnine forms 5-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-2H-1,3-methylenedioxy-[4,5-g]isoquinolinyl-1)barbituric acids, a new class of zwitter-ions, the structure of which was studied by 1H and 13C NMR spectroscopy and mass spectrometry. The prepared compounds exist in solution as stable intermolecular associates and have a complicated H-bonded structure.