31590-69-9Relevant academic research and scientific papers
Deuterium labelling evidence for a hydride mechanism in the formation of methyl propanoate from carbon monoxide, ethene and methanol catalysed by a palladium complex
Eastham, Graham R.,Tooze, Robert P.,Kilner, Melvyn,Foster, Douglas F.,Cole-Hamilton, David J.
, p. 1613 - 1617 (2002)
Reaction of ethene with CO in CH3OD in the presence of a catalyst prepared in situ from [Pd(DBPMB)(DBA)] (DBPMB = 1,2-bis[(di-tert-butyl)phosphinomethyl]benzene, DBA = dibenzylideneacetone) and methanesulfonic acid under conditions of good gas mixing gives a 1:1 mixture of CH2DCH2CO2Me and CH3CHDCO2Me with no H incorporated into the CH3OD. If the gas mixing is less efficient, the methyl propanoate has 0-5 D atoms incorporated in the ethyl group, CH3OD exchanges to give increasing amounts of CH3OH throughout the reaction and there is a slight increase in the less deuteriated products with reaction time. Significant D incorporation into unreacted ethene is also observed. These results are interpreted in terms of a hydride mechanism with the rates of the individual steps under conditions of good mixing being: reversible H migration to coordinated ethene > CO coordination ? C2H4 exchange > H/D exchange.
