31591-75-0Relevant academic research and scientific papers
Palladium-catalyzed aminocarbonylation of alkynes to succinimides
Liu, Huizhen,Lau, Genevieve P. S.,Dyson, Paul J.
, p. 386 - 391 (2015)
Succinimide derivatives are useful building blocks for the synthesis of natural products and drugs. We describe an efficient route to succinimide derivatives comprising Pd(xantphos)Cl2-catalyzed aminocarbonylation of alkynes with aromatic or aliphatic amines in the presence of p-TsOH. The utility of this route is demonstrated with the synthesis of a large number of succinimide compounds including an important photochromic molecule.
Synthesis and anticonvulsant properties of new 1-phenyl and 1-phenylamino-3-phenylpyrrolidine-2,5-dione derivatives
Obniska, Jolanta,Zejc, Alfred,Zagorska, Agnieszka
, p. 209 - 213 (2007/10/03)
A series of N-aryl and N-aminoaryl 3-phenyl pyrrolidine-2,5-diones were synthesized and tested for anticonvulsant activity in the maximum electroshock seizure (MES) and pentetrazol seizure threshold (sc Met) tests. Structures of the novel compounds were c
