31598-92-2

Usage

Uses

Used in Organic Synthesis:
[(2-chloro-2-phenylethenyl)sulfonyl]benzene is utilized as a building block in the creation of different organic compounds. Its unique structure, which includes a sulfonyl group and a chlorine atom, allows for a wide range of chemical reactions and modifications, making it a valuable component in the synthesis of complex molecules.
Used in Pharmaceutical Research:
[(2-chloro-2-phenylethenyl)sulfonyl]benzene has been studied for its potential pharmacological activities, indicating that it may have applications in the development of new drugs or therapies. However, further research is necessary to fully understand its properties and potential uses in this field.
Used in Chemical Industry:
Given its structural characteristics, [(2-chloro-2-phenylethenyl)sulfonyl]benzene may also find applications in the chemical industry for the production of various chemicals and materials. Its versatility in chemical reactions could make it a useful intermediate in the synthesis of specialty chemicals.
Safety Considerations:
It is crucial to handle and use [(2-chloro-2-phenylethenyl)sulfonyl]benzene with caution, as it may pose certain hazards to human health and the environment. Proper safety measures and guidelines should be followed to minimize any potential risks associated with its use.

Upstream product

• 536-74-3 phenylacetylene 
• 98-09-9 benzenesulfonyl chloride 
• 3406-03-9 2-(phenylsulfonyl)acetophenone 
• 80-17-1 benzenesufonyl hydrazide 
• 108-98-5 thiophenol 
• 873-55-2 sodium benzenesulfonate 
• 931-59-9 benzenesulfenyl chloride 

Downstream Products

• 27846-25-9 1-phenyl-2-(phenylsulfonyl)ethane 
• 98496-53-8 1-((E)-2-Benzenesulfonyl-1-phenyl-vinylsulfanyl)-4-bromo-benzene 
• 98496-62-9 1-((E)-2-Benzenesulfonyl-1-phenyl-ethenesulfonyl)-4-bromo-benzene 
• 98496-61-8 1-((E)-2-Benzenesulfonyl-1-phenyl-ethenesulfonyl)-4-chloro-benzene 
• 98496-60-7 (E)-(1-phenylethene-1,2-diyldisulfonyl)dibenzene 
• 92357-67-0 1-((E)-2-Benzenesulfonyl-1-phenyl-ethenesulfonyl)-4-methyl-benzene 
• 98496-54-9 2-((E)-2-Benzenesulfonyl-1-phenyl-vinylsulfanyl)-phenylamine 
• 98496-52-7 1-((E)-2-Benzenesulfonyl-1-phenyl-vinylsulfanyl)-4-chloro-benzene 
• 98496-51-6 (E)-(1-phenyl-2-(phenylsulfonyl)vinyl)(p-tolyl)sulfane 
• 98496-50-5 (E)-phenyl(1-phenyl-2-(phenylsulfonyl)vinyl)sulfane 

Relevant academic research and scientific papers

Iron(III) Chloride-Mediated Regio- and Stereoselective Chlorosulfonylation of Alkynes and Alkenes with Sodium Sulfinates

The atom-economic and one-pot regio- and stereoselective addition of sodium arenesulfinates to either alkynes or alkenes can be achieved with an iron(III) chloride hexahydrate [FeCl3?6 H2O] catalytic system to afford β-haloalkenyl and β-chloroalkyl sulfones in moderate to good yields. (Figure presented.).

A method of preparing beta-chloroalkenyl sulfone compounds from sulfonates and alkynes

A method of preparing beta-chloroalkenyl sulfone compounds from sulfonates and alkynes is provided. The method includes directly synthesizing the beta-chloroalkenyl sulfone compounds from the sulfonates and the alkynes in a nitrogen or inert gas atmosphere by using an iron halogenide agent. The method adopts raw materials and the iron halogenide agent which are cheap, stable and easily available, and does not use ligands, acids, peroxides, microwave radiation, and other special reaction conditions. Pre-functionalization of a substrate is not needed. The method is mild in reaction conditions, simple in operation, short in reaction time and high in product selectivity, substrate applicability and yield, and has a potential application prospect in the fields of medicines, organic synthesis intermediates, and the like.

Iron-Induced regio- and stereoselective addition of sulfenyl chlorides to alkynes by a radical pathway

The radical addition of the ClS s-bond in sulfenyl chlorides to various C~C triple bonds has been achieved with excellent regio- and stereoselectivity in the presence of a catalytic amount of a common iron salt. The reaction is compatible with a variety of functional groups and can be scaled up to the gram-scale with no loss in yield. As well as terminal alkynes, internal alkynes underwent stereodefined chlorothiolation to provide tetrasubstituted alkynes. Preliminary mechanistic investigations revealed a plausible radical process involving a sulfur-centered radical intermediate via iron-mediated homolysis of the ClS bond. The resulting chlorothiolation adducts can be readily transformed to the structurally complex alkenyl sulfides by cross-coupling reactions. The present reaction can also be applied to the complementary synthesis of the potentially useful bis-sulfoxide ligands for transition-metal-catalyzed reactions.

Iron halide-mediated regio- and stereoselective halosulfonylation of terminal alkynes with sulfonylhydrazides: Synthesis of (E)-β-chloro and bromo vinylsulfones

Halosulfonylation of terminal alkynes was achieved with sulfonylhydrazides as the sulfonyl precursor and inexpensive iron halide as halide source in the presence of TBHP, allowing the regio- and stereoselective generation of (E)-β-chloro and bromo vinylsu