31609-82-2Relevant articles and documents
3, 5-disubstituted isoxazole derivative and synthesis method thereof
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Paragraph 0011; 0023; 0040, (2021/08/14)
The invention provides a 3, 5-disubstituted isoxazole derivative and a synthesis method thereof, and belongs to the technical field of organic synthesis medicines and medical intermediates. The method comprises the following steps: adding a proper solvent
Direct synthesis of 4-fluoroisoxazoles through gold-catalyzed cascade cyclization-fluorination of 2-alkynone O-methyl oximes
Jeong, Yunkyung,Kim, Bom-I,Lee, Jae Kyun,Ryu, Jae-Sang
, p. 6444 - 6455 (2014/08/05)
A tandem protocol for the synthesis of fluorinated isoxazoles has been developed via catalytic intramolecular cyclizations of 2-alkynone O-methyl oximes and ensuing fluorination. The reactions proceed smoothly at room temperature in the presence of 5 mol
BENZO-γ-PYRONES. PART VIII. REACTION OF CHALCONE DIBROMIDES AND β-DIKETONES WITH HYDROXYLAMINE
Maib, Piotr,Basinski, Wlodzimierz,Jerzmanowska, Zofia
, p. 949 - 956 (2007/10/02)
In the reaction of some chalcone dibromides and unsymmetrically substituted diaroylmethanes with hydroxylamine formation of mixture of isomeric isoxazoles was observed and the percentage content of each isomer was established.A new mechanism is proposed for the reaction of β-diketones with hydroxylamine, based on enolic form in accordance with expected substituents effect.