31633-84-8Relevant articles and documents
Synthesis and SAR study of diphenylbutylpiperidines as cell autophagy inducers
Chen, Gang,Xia, Hongguang,Cai, Yu,Ma, Dawei,Yuan, Junying,Yuan, Chengye
scheme or table, p. 234 - 239 (2011/02/26)
A novel series of diphenylbutylpiperidines as autophagy inducers was described and extensive SAR studies resulted in derivatives (15d-e, 15i-j) with 10-fold greater activity than the lead compounds 1 and 2. Meanwhile, a new synthetic route to diphenylbutyl bromide (6) from bromobenzene and γ-butyrolactone was also reported here.
Identification of novel allosteric nonpeptidergic inhibitors of the human cytomegalovirus-encoded chemokine receptor US28
Vischer, Henry F.,Hulshof, Janneke W.,Hulscher, Saskia,Fratantoni, Silvina A.,Verheij, Mark H.P.,Victorina, Jane,Smit, Martine J.,de Esch, Iwan J.P.,Leurs, Rob
experimental part, p. 675 - 688 (2010/04/29)
Human cytomegalovirus (HCMV) is a widespread human pathogen, possessing onco-modulatory properties. Constitutive signaling of the HCMV-encoded chemokine receptor US28 and its ability to bind a broad spectrum of chemokines might facilitate HCMV-associated
