316375-85-6

Basic information

• Product Name: Methyl indolizine-1-carboxylate
• Synonyms: methyl indolizine-1-carboxylate;1-Indolizinecarboxylic acid methyl ester;1-carbomethoxyindolizine;Indolizine-1-carboxylic acid methyl ester
• CAS NO: 316375-85-6
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.18
• Mol File: 316375-85-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Density: 1.16
• Refractive Index: 1.573
• CAS DataBase Reference: Methyl indolizine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl indolizine-1-carboxylate(316375-85-6)
• EPA Substance Registry System: Methyl indolizine-1-carboxylate(316375-85-6)

Safety Data

• Hazardous Substances Data: 316375-85-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 28, p. 45, 1991 DOI: 10.1002/jhet.5570280108

InChI:InChI=1/C10H9NO2/c1-13-10(12)8-5-7-11-6-3-2-4-9(8)11/h2-7H,1H3

Upstream product

• 6266-23-5 1-(carboxymethyl)pyridinium chloride 
• 292638-85-8 acrylic acid methyl ester 
• 110-86-1 pyridine 
• 45811-13-0 N-(hydroxycarbonylmethyl)pyridinium bromide 
• 3724-55-8 methyl but-3-enoate 

Downstream Products

• 944405-43-0 methyl 3-(phenylethynyl)indolizine-1-carboxylate 
• 189569-52-6 methyl 3-(1-phenylvinyl)indolizine-1-carboxylate 
• 189569-63-9 (E)-methyl 3-styrylindolizine-1-carboxylate 
• 1200204-43-8 methyl 3-(1-(4-chlorophenyl)vinyl)indolizine-1-carboxylate 
• 1200204-29-0 methyl 3-(1-(4-methoxyphenyl)vinyl)indolizine-1-carboxylate 
• 1200204-35-8 methyl 3-(1-p-tolylvinyl)indolizine-1-carboxylate 
• 1200204-37-0 methyl 3-(1-m-tolylvinyl)indolizine-1-carboxylate 
• 1200204-45-0 methyl 3-(1-(4-fluorophenyl)vinyl)indolizine-1-carboxylate 
• 1200204-41-6 methyl 3-(1-(4-bromophenyl)vinyl)indolizine-1-carboxylate 
• 1200204-39-2 methyl 3-(1-o-tolylvinyl)indolizine-1-carboxylate 
• 1200204-31-4 methyl 3-(1-(4-tert-butylphenyl)vinyl)indolizine-1-carboxylate 
• 1200204-49-4 methyl 3-(1-(2-fluorophenyl)vinyl)indolizine-1-carboxylate 
• 1200204-33-6 methyl 3-(1-(2,4-dimethylphenyl)vinyl)indolizine-1-carboxylate 
• 1200204-51-8 methyl 3-(1-(naphthalen-2-yl)vinyl)indolizine-1-carboxylate 

Relevant articles and documents

Visible-Light-Induced Regioselective Dicarbonylation of Indolizines with Oxoaldehydes via Direct C-H Functionalization

A metal-free system for regioselective dehydrogenative cross-couplings between indolizines and oxoaldehydes catalyzed by visible light under mild conditions has been described. As an atom economical and eco-friendly protocol, the reaction proceeds in good yields using inexpensive, readily available visible-light sources and the environmentally friendly oxidant oxygen. Various valuable 1,2-dicarbonyl derivatives attached to an indolizine core were easily accessed by the direct dicarbonylation of the sp2 C-H bond.

INDOLIZINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds of formula (I) wherein Ra, Rb, Rc, Rd, T, R3, R4, R5, X, Y and Het are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.

PHOSPHATE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds of formula (I): wherein X, Y, A1, A2, Ra, Rb, Rc, Rd, R3, R4, T and R5 are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.