31638-54-7

Basic information

• Product Name: (1R-endo)-3-amino-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one hydrochloride
• Synonyms: (1R-endo)-3-amino-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one hydrochloride;(1R)-3-endo-AMinocaMphor Hydrochloride
• CAS NO: 31638-54-7
• Molecular Formula: C₁₀H₁₇NO*ClH
• Molecular Weight: 203.70902
• EINECS: 250-744-7
• Product Categories: Amines, Heterocycles
• Mol File: 31638-54-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 282.1°Cat760mmHg
• Flash Point: 124.4°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.00263mmHg at 25°C
• CAS DataBase Reference: (1R-endo)-3-amino-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (1R-endo)-3-amino-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one hydrochloride(31638-54-7)
• EPA Substance Registry System: (1R-endo)-3-amino-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one hydrochloride(31638-54-7)

Safety Data

• Hazardous Substances Data: 31638-54-7(Hazardous Substances Data)

Usage

Uses

(1R-endo)-3-amino-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one hydrochloride is used as a reactant for the synthesis of alpha-amino ketones.

InChI:InChI=1/C10H17NO.ClH/c1-9(2)6-4-5-10(9,3)8(12)7(6)11;/h6-7H,4-5,11H2,1-3H3;1H/t6-,7+,10+;/m1./s1

Upstream product

• 33162-63-9 3-endo-aminobornan-2-one 

Downstream Products

• 6610-21-5 6-methylcyclohex-2-en-1-one 
• 94167-43-8 6-Isopropenyl-6-methyl-cyclohex-2-en-1-on 
• 6069-78-9 Cyclocamphanon 
• 29900-93-4 (1R,2R,3S,4S)-3-Amino-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-ol 
• 13747-75-6 2-isopropenyl-2-methyl-cyclohexanone 
• 17206-50-7 2-Isopropyl-2-methyl-cyclohexanon 
• 13747-75-6 2β-Methyl-2α-isopropenyl-cyclohexanon 
• 133040-19-4 6β-Methyl-6α-isopropenyl-cyclohexen-(2)-on 

Relevant articles and documents

Asymmetric reduction of α-keto aldoxime o -ethers

The catalytic asymmetric reduction of -keto aldoxime O-methyl, O-benzyl, and O-trityl ethers, derived from substituted acetophenones, with borane/oxazaborolidines, by transfer hydrogenation, and with yeast, was studied. The reduction with borane/oxazaborolidines produced the corresponding -hydroxy oxime ethers, -hydroxy hydroxylamine ethers, and -amino alcohols in 39-78% yields and up to 77% ee. The carbonyl group was selectively reduced by transfer hydrogenation with formic acid-triethylamine catalyzed by RhCl[(R,R)-TsDPEN](Ce, and also with yeast, producing -hydroxy oxime ethers, up to 75% ee and 93% ee, respectively. Georg Thieme Verlag Stuttgart New York.