31646-29-4

Upstream product

• 21011-44-9 4-(4-chloro-thiobenzoyl)-morpholine 
• 74-88-4 methyl iodide 

Downstream Products

• 6265-91-4 2-(4-chlorophenyl)benzothiazole 
• 1141-35-1 2-(4-chlorophenyl)benzoxazole 
• 1019-85-8 2-(4-chlorophenyl)benzimidazole 
• 104-88-1 4-chlorobenzaldehyde 
• 120290-20-2 4-[(4-Chloro-phenyl)-methylsulfanyl-methyl]-morpholine 
• 31646-08-9 4-(4-Chloroselenobenzoyl)morpholine 
• 64906-20-3 (4-chloro-phenyl)-methylsulfanyl-morpholin-4-yl-acetonitrile 

Relevant academic research and scientific papers

Efficient one-step synthesis of benzazoles in aqueous media

Benzazoles (benzoxazoles, benzothiazoles, and benzimidazoles) were efficiently prepared by the aquatic reaction of the corresponding thioamidinium salts and 2-aminophenol, 2-aminothiophenol, and 1,2-diaminobenzene, respectively. The thioamidinium salt was successfully applied as an alternative to a carboxylic acid derivative to react smoothly with an amino precursor and in the presence of catalytic amounts of hexadecyltrimethylammonium bromide salt to produce benzazoles in good to excellent yields. Wiley-VCH Verlag GmbH & Co. KGaA 2009.

HIGHLY COORDINATE ORGANOSILICON COMPOUNDS IN SYNTHESIS: NEW ENTRY TO S,N-ACETALS BY SELECTIVE REDUCTION OF ALKYLTHIOMETHYLENIMINIUM SALTS BY USE OF TRIMETHOXYSILANE AND DILITHIUM 2,3-BUTANDIOLATE

Reduction of alkylthiomethyleniminium iodides proceeds smoothly by use of trimethoxysilane and dilithium 2,3-butandiolate in tetrahydrofuran at 0 deg C to give the corresponding S,N-acetals selectively in high yield.