6265-91-4

Usage

Uses

Used in Plastics Industry:
2-(4-CHLOROPHENYL)BENZOTHIAZOLE is used as a fluorescent brightener for improving the visual appeal and brightness of plastic materials. Its incorporation into plastics results in a more vibrant and attractive product.
Used in Fibers Industry:
In the fibers industry, 2-(4-CHLOROPHENYL)BENZOTHIAZOLE is used as a fluorescent brightening agent to enhance the color and brightness of synthetic fibers, making them more visually appealing and improving their marketability.
Used in Coatings Industry:
2-(4-CHLOROPHENYL)BENZOTHIAZOLE is used as a component in coatings to provide a brightening effect, enhancing the appearance of painted surfaces and offering improved aesthetic qualities.
Used in Inks Industry:
As a fluorescent brightener in inks, 2-(4-CHLOROPHENYL)BENZOTHIAZOLE helps to create more vivid and eye-catching printed materials, increasing their visual impact.
Used in Detergents Industry:
2-(4-CHLOROPHENYL)BENZOTHIAZOLE is used in detergents to brighten fabrics during the washing process, resulting in cleaner and more vibrantly colored textiles.
Used as a UV-protecting agent:
2-(4-CHLOROPHENYL)BENZOTHIAZOLE is utilized in various products as a UV-protecting agent to shield materials from the harmful effects of ultraviolet radiation, thereby extending their lifespan and maintaining their quality.

InChI:InChI=1/C13H8ClNS/c14-10-7-5-9(6-8-10)13-15-11-3-1-2-4-12(11)16-13/h1-8H

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 137-07-5 2-amino-benzenethiol 
• 5909-74-0 N-phenyl-C-(4-chlorophenyl)nitrone 
• 142505-38-2 N-(4-chlorophenylmethylene)-2-methylthiobenzenamine 
• 104-88-1 4-chlorobenzaldehyde 
• 14063-77-5 (Z)-3-chloro-3-(4-chlorophenyl)acrylaldehyde 
• 615-22-5 2-methylmercaptobenzothiazole 
• 17151-48-3 tributyl(4-chlorophenyl)stannane 
• 95-16-9 1,3-Benzothiazole 
• 106-39-8 bromochlorobenzene 
• 2005-08-5 4-chlorophenyl benzoate 
• 2516-40-7 2-bromo-1,3-benzothiazole 
• 1679-18-1 4-Chlorophenylboronic acid 
• 31646-29-4 4-[(4-chloro-phenyl)-methylsulfanyl-methylene]-morpholinium; iodide 

Downstream Products

• 134384-31-9 2-(4-trifluoromethylphenyl)benzothiazole 
• 6278-73-5 2-(4-aminophenyl)benzothiazole 
• 2548-64-3 2-(4-(benzothiazol-2-yl)phenyl)acetonitrile 
• 1007375-81-6 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzo-[d]thiazole 
• 17930-02-8 2-(4'-cyanophenyl)benzothiazole 
• 6265-55-0 2-(4-hydroxyphenyl)benzothiazole 
• 883-93-2 2-Phenylbenzothiazole 
• 6265-92-5 2-(4-methoxy-phenyl)-benzothiazole 
• 90481-40-6 2-(benzo[d]thiazol-2-yl)-5-chlorophenol 

Relevant academic research and scientific papers

Synthesis of 2-Arylbenzothiazoles from Nitrobenzenes, Benzylamines, and Elemental Sulfur via Redox Cyclization

A sustainable advanced synthetic method was developed based on redox cyclization for the synthesis of 2-arylbenzothiazoles in good to excellent yields from readily available nitrobenzenes, benzylamines, and elemental sulfur without the use of transition-metal catalysts. This method is remarkable: nitro group reduction, a benzylamine redox reaction, sulfuration, condensation, and cyclization, all proceed in a single step to generate a heterocycle. It is also highly atom-economical and does not require any external oxidizing or reducing agents.

Recyclable copper-catalyzed cyclization of o-haloanilides and metal sulfides: An efficient and practical access to substituted benzothiazoles

An efficient heterogeneous copper-catalyzed cyclization of o-haloanilides and metal sulfides has been achieved via the C–S coupling in DMF at 80 or 140 °C in the existence of an MCM-41-bound NHC-Cu(I) catalyst and then intramolecular condensation, delivering a wide range of substituted benzothiazoles in mostly good to high yields. This new MCM-41-NHC-CuI complex can facilely be obtained by a two-step procedure starting from easily accessible and inexpensive reagents and reused more than seven times without any significant loss of its catalytic efficiency. The present protocol has been successfully applied to the gram-scale synthesis of two antitumor agents 5F203 and PMX 610.

Graphene oxide-catalyzed synthesis of benzothiazoles with amines and elemental sulfur via oxidative coupling strategy of amines to imines

The graphene oxide-catalyzed coupling and cyclization reactions of primary amines with elemental sulfur was developed to afford various optically property benzothiazoles. This coupling and cyclization strategies proceeded under the oxidant system graphene oxide/O2 and constructed carbon-heteroatom (N, S) bonds with amines and elemental sulfur. Due to benzothiazoles as common chromophores, these products exhibited intriguing fluorescence properties, including outstanding Stokes shifts (up to 161 nm) and quantum yields (up to 74%). Utilizing the products’ unique fluorescence response in different solvents, β-naphthothiazole 4a showed excellent aggregation-induced emission properties in 1,2-dichloroethane, which was 60 times higher than in tetrahydrofuran.

Bis/hetero aromatic compound and preparation method thereof

The invention discloses a bi/hetero aromatic compound and a preparation method thereof. The structural formula of the bi/hetero aromatic compound is as shown in formula 3. The preparation method comprises the following steps: taking an aryl tetrafluorobor

Visible-Light Carbon Nitride-Catalyzed Aerobic Cyclization of Thiobenzanilides under Ambient Air Conditions

A metal-free heterogeneous photocatalysis has been developed for the synthesis of benzothiazoles via intramolecular C-H functionalization/C-S bond formation of thiobenzanilides by inexpensive graphitic carbon nitride (g-C3N4) under visible-light irradiation. This reaction provides access to a broad range of 2-substituted benzothiazoles in high yields under an air atmosphere at room temperature without addition of a strong base or organic oxidizing reagents. In addition, the catalyst was found to be stable and reusable after five reaction cycles.

KOtBu-Promoted Halogen-Bond-Assisted Intramolecular C-S Cross-Coupling of o-Iodothioanilides for the Synthesis of 2-Substituted Benzothiazoles

An efficacious and mild KOtBu-promoted intramolecular C-S cross-coupling of ortho-iodothioanilides in conjunction with a catalytic quantity of phenanthroline as an additive has been described for the convenient synthesis of 2-substituted benzothiazoles. The methodology is suitable for attaining a wide variety of 2-alkyl- and 2-aryl-substituted benzothiazoles. Single-crystal XRD, DFT calculations, NMR, and UV studies suggest that halogen bonds between the units of ortho-iodothioanilides may assist in the electron transfer process.

Photocatalyst- And Transition-Metal-Free Visible-Light-Promoted Intramolecular C(sp2)-S Formation

A photocatalyst- and transition-metal-free visible-light-induced cyclization of ortho-halothiobenzanilides has been developed. Upon irradiation with visible light, substrates undergo dehalogenative cyclization to 2-aryl benzothiazoles with high efficiency and selectivity. This photocyclization exhibits a high tolerance to various functional groups, is applicable for the synthesis of 2-alkyl benzothiazoles, and is easy to set up for gram-scale reaction.

Preparation method of benzothiazole phosphate compound

The invention discloses a preparation method of a benzothiazole phosphate compound. Under the irradiation of visible light, N-(2-bromophenyl) alkyl thioamide such as N-(2-bromophenyl) alkyl thioamide derivatives and the like are used as raw materials, sodium phosphate is used as alkali, a series of 2-substituted alkyl benzothiazole derivatives are smoothly synthesized, and further, under the irradiation of visible light, the benzothiazole phosphate compound is prepared through reaction with diethyl phosphate, and the benzothiazole phosphate compound has the calcium antagonist capability.

Method for preparing benzothiazole compound from visible light promoted N-(2-bromophenyl) thioamide

The invention discloses a method for preparing a benzothiazole compound from N-(2-bromophenyl) thioamide under the promotion of visible light. Specifically, under the protection of inert gas, according to the molar ratio of N-(2-bromophenyl) thioamide to inorganic base being 1: 0.5, reactants are added into a reaction container provided with a stirring device, then dimethyl sulfoxide is added, and stirring reaction is carried out for 2-24 hours at room temperature under the irradiation of visible light to obtain the benzothiazole compound. Under the condition of not adding any photosensitizer or transition metal catalyst, sodium phosphate is used as alkali, and under the irradiation of a 45W household compact fluorescent lamp, a series of intramolecular cross-coupling reactions of N-(2-bromophenyl) thioamide are realized. In addition, the benzothiazole compound can be obtained with high yield. The whole process is green, efficient and easy to operate, and the method is a good method for synthesizing the benzothiazole compound.

Method for preparing biphenyl benzothiazole compound

The invention discloses a preparation method of a biphenyl benzothiazole compound. N-(2-bromophenyl) alkyl thioamide such as an N-(2-bromophenyl) alkyl thioamide derivative is used as a raw material, sodium phosphate is used as alkali, the biphenyl benzothiazole compound is prepared through a one-pot method, the reaction is carried out under visible light irradiation, metal ions disclosed in the prior art are not needed, and the reaction yield is high.