31679-13-7Relevant academic research and scientific papers
Are multicomponent strecker reactions of diketones with diamines under high pressure amenable to heterocyclic synthesis?
Kumamoto, Koji,Iida, Hirokazu,Hamana, Hiroshi,Kotsuki, Hiyoshizo,Matsumoto, Kiyoshi
, p. 675 - 681 (2007/10/03)
Employing double Strecker strategy, two new heterocyclic compounds, 5,6,11,12-tetrahydro-6,11-dimethyldibenzo[b,f][1,4]diazocine-6,11-dicarbonitrile and 1,2,3,4,5,10-hexahydrophenazine-4a, 10a-dicarbonitrile, were prepared in one step albeit in low yields. The reaction has proven to be very limited, but such a sterically hindered amine as N-methylaniline underwent Strecker reaction with benzaldehyde and TMSCN to give the corresponding α-amino nitriles.
Copper (I) 1,3-R2-3,4,5,6-tetrahydropyrimidin-2-ylidenes (R=mesityl, 2-propyl): Synthesis, X-ray structures, immobilization and catalytic activity
Bantu, Bhasker,Wang, Dongren,Wurst, Klaus,Buchmeiser, Michael R.
, p. 12145 - 12152 (2007/10/03)
The synthesis of novel copper (I) N-heterocyclic carbene complexes is described. Thus, reaction of CuX with 1,3-di(2-propyl)-3,4,5,6- tetrahydropyrimidin-2-ylidene yields CuX(1,3-di(2-propyl)-3,4,5,6- tetrahydropyrimidin-2-ylidene) (X=Cl, (1a), Br (1b));
Synthesis of fluoroorganic O-(Trirnethylsilyl)cyanhydrines
Sander, Michael,Sundermeyer, Wolfgang
, p. 296 - 306 (2007/10/03)
Fluororganic and/or sterically hindered cyanohydrines are useful synthetic reagents, not readily available directly from e.g. aldehydes or ketones and hydrogen cyanide. By using trimethylsilyl cyanide (TMSCN), the obtained O-Silyl-cyanohydrines can be app
On the Preparation of Acyl Cyanides from Aldehydes
Haerle, Helmut,Jochims, Johannes C.
, p. 1400 - 1412 (2007/10/02)
The O-silylated cyanohydrins 3 prepared from the aldehydes 1 with trimethylsilyl cyanide are oxidized photochemically or thermally with N-bromosuccinimide to afford the acyl cyanides 4a-n.Scope and limitations of the procedure are discussed.
