31680-07-6

Usage

Uses

Used in Organic Synthesis:
4-Methyl-3-nitrobenzaldehyde is used as a key intermediate for the synthesis of various organic compounds, contributing to the formation of complex molecules and enhancing the diversity of chemical products.
Used in Pharmaceuticals:
In the pharmaceutical industry, 4-Methyl-3-nitrobenzaldehyde is utilized as a crucial building block in the development of new drugs, playing a significant role in medicinal chemistry and drug discovery.
Used in Agrochemicals:
4-Methyl-3-nitrobenzaldehyde is employed as a vital component in the production of agrochemicals, such as pesticides and herbicides, helping to improve agricultural productivity and crop protection.
Used in Dye Industry:
In the dyestuff sector, 4-Methyl-3-nitrobenzaldehyde is used as a raw material for the synthesis of various dyes and pigments, contributing to the coloration and appearance of textiles, plastics, and other materials.

InChI:InChI=1/C8H7NO3/c1-6-2-3-7(5-10)4-8(6)9(11)12/h2-5H,1H3

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 40870-59-5 (4-Methyl-3-nitro-phenyl)-methanol 
• 106-42-3 para-xylene 
• 7664-93-9 sulfuric acid 
• 7697-37-2 nitric acid 
• 96-98-0 4-methyl-3-nitrobenzoic acid 
• 541-41-3 chloroformic acid ethyl ester 
• 108-88-3 toluene 

Downstream Products

• 35781-34-1 4-methyl-3-nitro-cinnamic acid 
• 132390-58-0 4-methyl-3-nitro-chalcone 
• 100726-38-3 2-(4-methyl-3-nitro-phenyl)-1H-benzimidazole 
• 108718-77-0 1-methyl-2-(4-methyl-3-nitro-phenyl)-5-nitro-1H-benzimidazole 
• 3001-05-6 4-Methyl-3,4'-dinitro-trans-stilben 
• 2571-11-1 (E) 4'-methyl-2,3',4-trinitrostilbene 
• 2571-42-8 4-Cyan-4'-methyl-2,3'-dinitro-trans-stilben 
• 2913-87-3 4,5'-Dimethyl-2',3,4'-trinitro-trans-stilben 
• 162705-18-2 (Z)-3-(3-nitro-4-methylphenyl)-2-(3,4,5-trimethoxyphenyl)-prop-2-ene-nitrile 
• 939-79-7 4-cyano-2-nitrotoluene 
• 676260-08-5 4-ethynyl-1-methyl-2-nitrobenzene 

Relevant academic research and scientific papers

Diarylurea-linked zinc porphyrin dimer as a dual-mode artificial receptor: Supramolecular control of complexation-facilitated photoinduced electron transfer

A novel porphyrinic receptor 1 in which two zinc porphyrins are bridged by two diarylurea linkers was developed for recognition of a viologen derivative (hexyl viologen, HV). The electronic absorption spectra as well as the 1H NMR experiments revealed that the HV molecule was bound to the cleft in 1 mainly through carbonyl dipole-charge interactions to afford a 1:1 complex. From the steady-state fluorescence spectroscopic study, the photoinduced electron transfer (PET) from 1 to HV was extremely facilitated by the receptor-substrate complexation. The receptor 1 also formed a 1:1 complex with 1,4-diazabicyclo[2.2.2]octane (DABCO) through two Zn-N coordination interactions, and, using DABCO as an inhibitor, we suppressed the PET reaction via the substrate exchange. Copyright

HETEROARYL COMPOUNDS AS INHIBITORS OF PROGRAMMED NECROSIS PATHWAY, COMPOSITION AND METHOD USING THE SAME

The present disclosure provides heteroaryl compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to the programmed necrosis pathway.

INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES

The present invention relates to novel aryl isoxazoline derivatives having excellent insecticidal activity as insecticides and represented by the formula: and their use as insecticides and acarizides.

Benzoxazepinones and their use as squalene synthase inhibitors

There is disclosed a compound represented by the formula [I]: wherein R1 is optionally substituted 1-carboxyethyl group, optionally substituted alkyl-sulfonyl group, optionally substituted (carboxy-cycloalkyl)-alkyl group, -X1-X2-Ar-X3-X4-COOH (wherein X1 and X4 are a bond or alkylene group, X2 and X3 are a bond, -O-, -S-, Ar is divalent aromatic group etc.), R2 is alkyl group optionally substituted with alkanoyloxy group and/or hydroxy group, R3 is alkyl group, and W is halogen atom, etc., or a salt thereof. The compound has the cholesterol lowering activity and the triglyceride lowering activity and is useful for preventing and/or treating hyperlipidemia.

Synthesis and structure-activity relationships of 2-(substituted phenyl)-3-[3-(N,N-dimethylamino)propyl]-1,3-thiazolidin-4-ones acting as H1-histamine antagonists

2-(Substituted-phenyl)-3-[3-(N,N-dimethylamino)propyl]-1,3-thiazolidin-4-ones (1-15) showed dependence of the potency of the H1-histamine antagonism on the m- and p-substituents suggesting that the aromatic moiety binds the receptor by a strong

Benzopyridazinone and pyridopyridazinone compounds

Benzo or pyridopyridazinones and pyridazinthiones of the formula STR1 wherein: X and Y are nitrogen or carbon, provided that at least one is carbon, and Z is oxygen or sulfur; R1 is hydrogen, lower alkyl, aryl, aralkyl, heterocyclo, heterocyclo lower-alkyl, heteroaryl, or heteroaralkyl; R2, R3, R4, R5 and R6 are independently selected from hydrogen, lower alkyl, halo, carboxy, alkoxycarbonyl, carbamoyl, lower-alkyl carbonyl, halocarbonyl, thiomethyl, trifluoromethyl, cyano or nitro; or a pharmaceutically acceptable ester, ether or salt thereof, have been found to be useful as an anti-inflammatory, antasthmatic, immunosuppressive, anti-allograft rejection, anti-graft-vs-host rejection, autoimmune disease or analgetic agent(s).

The Chemistry of Indoles. XXXII. A Facile Synthetic Method for 6-Indolecarbaldehyde, 6-Indolemethanol, and 6-Substituted 1-Hydroxyindoles and Its Application for the Synthesis of a Natural Alkaloid, (E)-6-(3-Methylbuta-1,3-dienyl)indole

Trivalent titanium ion can reduce arylaldehydes, and the reaction is controllable by selecting the pH of the reaction medium.Utilizing this new finding, 6-indolecarbaldehyde and 6-indolemethanol were conveniently produced by the modified Leimgruber-Batcho method with titanium(III) chloride as the reducing agent.Syntheses of a natural alkaloid, (E)-6-(3-methylbuta-1,3-dienyl)indole, and some new 6-substituted 1-hydroxyindoles are also reported.Keywords-titanium(III) chloride; 6-indolecarbaldehyde; 6-indolemethanol; (E)-6-(3-methylbuta-1,3-dienyl)indole; (Z)-6-(3-methylbuta-1,3-dienyl)indole; 1-hydroxy-6-indolecarbaldehyde; 1-methoxy-6-indolecerbaldehyde; 1-acetoxy-6-indolecarbaldehyde; Leimgruber-Batcho method; reduction

Magenta dye developers

Diffusion transfer color processes and products are disclosed employing image-dye providing materials providing magenta image dyes having the chromophoric system represented by the formula STR1 wherein each R is the same or different and is an alkyl group, and each X is the same or different and is hydrogen or an alkyl group (including substituted alkyl). The dye image-providing material includes a diffusion control moiety, such as a hydroquinonyl group, and may be diffusible or nondiffusible as a function of the diffusion control moiety.

Process for the production of nitro derivatives of aromatic compounds

Nitroderivates of aromatic compounds which are difficult to nitrate, can readily be obtained by nitration providing that the aromatic compound is treated with nitric acid or another nitrating agent in the presence of aliphatic or cycloaliphatic hydrocarbons monosubstituted or polysubstituted by halogen, the nitro group or an alkyl sulphonyl group, and the nitro derivative formed subsequently isolated.