316804-22-5Relevant articles and documents
Synthesis of kanamycin A analogs containing a 6-amino-6-deoxyglycofuranose moiety
Kobayashi, Yoshihiko,Ohgami, Tetsuro,Ohtsuki, Katsura,Tsuchiya, Tsutomu
, p. 325 - 340 (2007/10/03)
Three kanamycin A analogs containing 6-amino-6-deoxyglycofuranoses have been prepared as candidates for potential activity against resistant bacteria producing 6'-N-acetyltransferase. They are 4-O-(6-amino-3,5,6-trideoxy-α-D-, -β-D-, and -β-L-erythro-hexofuranosyl)-6-O-(3-amino-3-deoxy-α-D-glucopyran osyl)-2,5-dideoxy-5-epi-5-fluorostreptamine. Structure-activity relationships of these compounds are discussed. (C) 2000 Published by Elsevier Science Ltd.