316821-35-9

Upstream product

• 100-46-9 benzylamine 
• 144492-44-4 (R)-4-[(E)-Benzylimino-methyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 112674-71-2 (R)-(2-oxo-4-phenyl-1,3-oxazolidin-3-yl)acetyl chloride 
• 317815-80-8 3-formyl-8-(4-hydroxy-phenyl)-1-oxa-4-aza-spiro[4.5]decane-4-carboxylic acid tert-butyl ester 
• 144541-27-5 cis-(3R,4S)-1-benzyl-3-<(R)-2-oxo-4-phenyloxazolidin-3-yl>-4-<(R)-3-<(tert-butoxycarbonyl)amino>-2,2-dimethyloxazolidin-4-yl>azetidin-2-one 

Downstream Products

• 135821-30-6 (4R,3'R,4'R)-3-<4'-(hydroxymethyl)-2'-oxo-1'-(phenylmethyl)-3'-azetidinyl>-4-phenyl-2-oxazolidinone 
• 110289-27-5 cis-(3R,4R)-1-benzyl-4-formyl-3-<(4R)-2-oxo-4-phenyloxazolidin-3-yl>azetidin-2-one 

Relevant academic research and scientific papers

A stereoselective synthesis of 1,3,4-substituted β-lactams from polymer-supported chiral oxazolidine aldehyde

The synthesis of a polymer supported chiral oxazolidine aldehyde is described. This intermediate has great potential for the synthesis of biologically interesting compounds. A solid phase stereoselective synthesis of an array of chirally pure β-lactams in high purity is described as a first application of the system. (C) 2000 Elsevier Science Ltd.