31688-50-3Relevant academic research and scientific papers
Cobaloxime-Catalyzed Radical Alkyl-Styryl Cross Couplings
Branchaud, Bruce P.,Detlefsen, William D.
, p. 6273 - 6276 (1991)
Cobaloxime-catalyzed radical alkyl-styryl cross couplings can be accomplished by visible light photolysis of various alkyl bromides + styrene + in-situ-generated CoII(dmgH)2py + Zn in refluxing CH3CN or refluxing 95percentEtOH.cobaloximes; radi
Visible Light-Induced Room-Temperature Heck Reaction of Functionalized Alkyl Halides with Vinyl Arenes/Heteroarenes
Kurandina, Daria,Parasram, Marvin,Gevorgyan, Vladimir
supporting information, p. 14212 - 14216 (2017/10/13)
The first visible light-induced Pd-catalyzed Heck reaction of α-heteroatom substituted alkyl iodides and -bromides with vinyl arenes/heteroarenes has been developed. This transformation efficiently proceeds at room temperature and enables synthesis of valuable functionalized allylic systems, such as allylic silanes, boronates, germanes, stannanes, pivalates, phosphonates, phthalimides, and tosylates from the corresponding α-substituted methyl iodides. Notably, synthesis of the latter substrates failed under existing thermally induced Pd-catalyzed conditions, which highlights the importance of visible light for this transformation.
