317-52-2 Usage
Originator
Mylaxen,Mallinckrodt
Uses
Different sources of media describe the Uses of 317-52-2 differently. You can refer to the following data:
1. Relaxant (skeletal muscle); synergist (succinylcholine).
2. Hexafluorenium Bromide is a cholinesterase inhibitor.
Manufacturing Process
2 Methods of producing of hexamethylene bis(2-fluorenyldimethylammonium)
dibromide:
1. To a solution of 13.2 g (0.054 mole) of 9-bromofluorene in 200 ml of
acetonitrile was added 3.1 g (0.018 mole) of 1,6-bis(dimethylamino)hexane.
Heat was evolved and solid began to precipitate immediately. After the initial
reaction had subsided the mixture was refluxed for 3.5 h on a steam bath.
The solid was collected and recrystallized three times from propanol to give
10.66 g (89% of the theoretical yield based on alkylenediamine) of
hexamethylene bis(9-fluorenyldimethylammonium) dibromide, as white
crystals melting at 188°-189°C.
2. A mixture of 4.18 g (0.02 mole) of 2-dimethylaminofluorene and 1.22 g
(0.005 mole) of 1,6-dibromohexane was heated at 115°C for 24 h, after
which time 10 ml of dry dioxane was added and the mixture refluxed for an
additional 37 h. The solid was filtered off washed with hot acetonitrile and
twice recrystallized from propanol to give 0.45 g of hexamethylene bis(2-
fluorenyldimethylammonium) dibromide, melting at 220°-222°C.
Brand name
Mylaxen (Medpointe).
Therapeutic Function
Muscle relaxant
Check Digit Verification of cas no
The CAS Registry Mumber 317-52-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,1 and 7 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 317-52:
(5*3)+(4*1)+(3*7)+(2*5)+(1*2)=52
52 % 10 = 2
So 317-52-2 is a valid CAS Registry Number.
InChI:InChI=1/C36H42N2.2BrH/c1-37(2,35-31-21-11-7-17-27(31)28-18-8-12-22-32(28)35)25-15-5-6-16-26-38(3,4)36-33-23-13-9-19-29(33)30-20-10-14-24-34(30)36;;/h7-14,17-24,35-36H,5-6,15-16,25-26H2,1-4H3;2*1H/q+2;;/p-2
