31709-15-6Relevant articles and documents
Mononuclear Heterocyclic Rearrangements. Effect of the Structure of the Side Chain on the Reactivity. Part 3. Rearrangement of Some N-(5-phenyl-1,2,4-oxadiazol-3-yl)-N'-arylformamidines into 1-Aryl-3-benzoylamino-1,2,4-triazoles in Acetonitrile in the Presence of Triethylamine
Frenna, Vincenzo,Macaluso, Gabriella,Vivona, Nicolo,Spinelli, Domenico,Consiglio, Giovanni,Mezzina, Elisabetta
, p. 7315 - 7326 (2007/10/02)
The apparent pseudo-first-order rate constants for the title reaction give a curvilinear plot versus tertiary amine concentration, according to the equation kA=(ku+K1k2)/(1+K1).This shows the occurrence of two different reaction pathways; the one, independent of and the other, dependent on , which involves a fast conversion of the substrate into an acid-base adduct or an ion pair followed by its slow conversion into the corresponding triazole.The substituent effects on these reactions have also been studied.