3172-34-7Relevant academic research and scientific papers
Nickel-Catalyzed Reaction of Aryl 2-Pyridyl Ethers with Silylzinc Chlorides: Silylation of Aryl 2-Pyridyl Ethers via Cleavage of the Carbon?Oxygen Bond
Kong, Ying-Ying,Wang, Zhong-Xia
supporting information, p. 5440 - 5448 (2019/11/16)
Ni-catalyzed C?O(Py) bond activation and silylation of aryl 2-pyridyl ethers with silylzinc chlorides were carried out. This protocol allowed the 2-pyridyloxy group to be substituted by a silyl group with short reaction times, mild reaction conditions, and good compatibility of functional groups. (Figure presented.).
Silyldefluorination of Fluoroarenes by Concerted Nucleophilic Aromatic Substitution
Mallick, Shubhadip,Xu, Pan,Würthwein, Ernst-Ulrich,Studer, Armido
supporting information, p. 283 - 287 (2018/12/13)
The reaction of readily generated silyl lithium reagents with various aryl fluorides to provide the corresponding aryl silanes is reported. DFT calculations reveal that the nucleophilic aromatic substitution of the fluoride anion by the silyl lithium reagent proceeds through concerted ipso substitution. In contrast to the classical nucleophilic aromatic substitution, this concerted ionic silyldefluorination also occurs on more electron-rich aryl fluorides.
