317319-35-0 Usage
General Description
The chemical 2-[2-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolecarboxylic acid ethyl ester is a compound with a complex molecular structure that includes a thiazole ring and a trifluoromethylphenyl group. It is derived from the parent compound thiazolecarboxylic acid and is in the form of an ethyl ester. This chemical is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals due to its versatile reactivity and potential for introducing fluorine atoms into target molecules. The presence of both fluorine and methyl groups in its structure makes it a useful component for drug discovery and development. Additionally, the incorporation of the thiazole ring provides unique pharmacological properties that make it an important target for drug synthesis and discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 317319-35-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,7,3,1 and 9 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 317319-35:
(8*3)+(7*1)+(6*7)+(5*3)+(4*1)+(3*9)+(2*3)+(1*5)=130
130 % 10 = 0
So 317319-35-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H11F4NO2S/c1-3-21-13(20)11-7(2)19-12(22-11)9-5-4-8(6-10(9)15)14(16,17)18/h4-6H,3H2,1-2H3
317319-35-0Relevant articles and documents
Process development for sodelglitazar: A ppar panagonist
Brown, Andrew D.,Davis, Roman D.,Fitzgerald, Russ N.,Glover, Bobby N.,Harvey, Kim A.,Jones, Lynda A.,Liu, Bing,Patterson, Daniel E.,Sharp, Matthew J.
experimental part, p. 297 - 302 (2010/04/22)
Three efficient syntheses of sodelglitazar (1) have been developed. In particular, the third synthesis avoids the use of zinc and eliminates the resulting heavy metal waste stream as well as the potential genotoxic methanesulfonate in the two earlier syntheses. This process produces sodelglitazar in 74% overall yield from readily available thiophenol (8) and thiazole alcohol (3).
