317335-16-3

Usage

General Description

Methyl-4-bromomethylpyridine-2-carboxylate is a chemical compound with the molecular formula C8H8BrNO2. It is a derivative of pyridine and contains a methyl ester and a bromomethyl functional group. METHYL-4-BROMOMETHYLPYRIDINE-2-CARBOXYLATE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is known for its reactivity and is used as a building block in organic synthesis. Methyl-4-bromomethylpyridine-2-carboxylate is also used in research and development for the creation of new chemical compounds. It is important to handle it with care as it can be hazardous if not properly managed.

InChI:InChI=1/C8H8BrNO2/c1-12-8(11)7-4-6(5-9)2-3-10-7/h2-4H,5H2,1H3

Upstream product

• 117423-41-3 4-((tert-butyldimethylsilyloxy)methyl)pyridine 
• 117423-42-4 4-<<(tert-butyldimethylsilyl)oxy>methyl>pyridine N-oxide 
• 117423-43-5 2-cyano-4-[{(tert-butyldimethylsilyl)oxy}methyl]pyridine 
• 586-95-8 pyridine-4-methanol 
• 13509-13-2 4-methylpyridine-2-carboxylic acid methyl ester 
• 317335-15-2 methyl 4-(hydroxymethyl)pyridine-2-carboxylate 

Downstream Products

• 1072707-62-0 methyl 4-(aminomethyl) pyridine-2-carboxylate 
• 1571023-14-7 1-{[2-(2-hydroxypropan-2-yl)pyridin-4-yl]methyl}-5-{3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl}-1,2-dihydropyridin-2-one 

Relevant academic research and scientific papers

HETEROCYCLIC MODULATORS OF HIF ACTIVITY FOR TREATMENT OF DISEASE

The present invention relates to compounds and methods which may be useful as inhibitors of HIF pathway activity for the treatment or prevention of cancer and other hypoxia-mediated diseases.

QUINAZOLINEDIONES AND THEIR USE

The present invention discloses compounds of formula (I), or pharmaceutically acceptable salts or prodrugs thereof, which inhibit the poly(ADP-ribose) polymerases (PARP) and therefore are useful for treating diseases, disorders, and conditions related to PARP. The present invention also discloses pharmaceutical compositions comprising a compound of formula (I), and methods of using such compounds to inhibit PARP enzymes, and to treat diseases, disorders, and conditions related to PARP.

ANTIVIRAL COMPOUNDS AND USE THEREOF

The invention relates to compounds, pharmaceutical compositions and methods useful for treating viral infection.

1-(Aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof

Certain 1-(aromatic- or heteroaromatic-substituted-3-(heteroaromatic substituted)-1,3-propanediones are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.