317339-60-9

Upstream product

• 947704-83-8 dihydropyridone bromide 
• 317339-57-4 4-phenylsulfanyl-1-(toluene-4-sulfonyl)-3,6-dihydro-1H-pyridin-2-one 
• 64741-13-5 3-thiophenyl-3-sulfolene 
• 4083-64-1 Tosyl isocyanate 

Downstream Products

• 411240-92-1 4-phenylsulfanyl-5,6-dihydro-1H-pyridin-2-one 
• 411240-90-9 4-benzyl-1-(toluene-4-sulfonyl)-5,6-dihydro-1H-pyridin-2-one 
• 1011302-76-3 5,6-dihydro-4-phenylsulfinyl-1-tosylpyridin-2(1H)-one 
• 317339-72-3 4-(phenylsulfonyl)-1-tosyl-5,6-dihydro-2-pyridone 
• 1356158-00-3 (E)-N-allyl-3-(phenylthio)-N-tosylpenta-2,4-dienamide 
• 1356157-96-4 (E)-N-methyl-3-(phenylthio)-N-tosylpenta-2,4-dienamide 
• 1356157-94-2 (E)-3-(phenylthio)-N-tosylpenta-2,4-dienamide 
• 1356158-31-0 2-benzoyl-7-(phenylthio)-2,3,3a,4,5,6-hexahydro-1H-isoindol-1-one 
• 1356158-29-6 2-benzyl-7-(phenylthio)-2,3,3a,4,5,6-hexahydro-1H-isoindol-1-one 
• 1356158-27-4 2-allyl-7-(phenylthio)-2,3,3a,4,5,6-hexahydro-1H-isoindol-1-one 
• 1356158-25-2 2-ethyl-7-(phenylthio)-2,3,3a,4,5,6-hexahydro-1H-isoindol-1-one 
• 1356158-19-4 2-methyl-7-(phenylthio)-2,3,3a,4,5,6-hexahydro-1H-isoindol-1-one 
• 1356158-15-0 7-(phenylthio)-2,3,3a,4,5,6-hexahydro-1H-isoindol-1-one 
• 1356158-05-8 7-(phenylthio)-2-tosyl-2,3,3a,4,5,6-hexahydro-1H-isoindol-1-one 

Relevant academic research and scientific papers

Indium-promoted Conversion of Allylic Bromide to Alcohol Moiety and Synthesis of Pipermethystine Skeletons

Dihydropyridone bromide (2) was converted to the corresponding alcohol (1) by reaction with indium in air or with indium followed by treatment with a sulfonyloxaziridine. The alcohol (1) was transformed in four steps to a phenylsulfone-substituted pipermethystine derivative (10). Reductive cleavage of the phenylsulfone did not yield the pipermethystine natural product. Several new pyridone derivatives were synthesized.

Cycloaddition reactions of 4-sulfur-substituted dihydro-2-pyridones and 2-pyridones with conjugated dienes

Cycloaddition reactions of sulfoxide- and sulfone-substituted dihydro-2-pyridones and 2-pyridones with electron-rich dienes gave new bicyclic and tricyclic products in good to fair yields. The reactivity, regioselectivity, and stereoselectivity of these r

Synthesis and applications of tetrahydro-2-pyridinones via aza-Diels - Alder reactions of thio-substituted 1,3-dienes with arylsulfonyl isocyanates

The first aza-Diels - Alder reactions of arylsulfonyl isocyanates with thio-substituted 1,3-dienes via the 3-sulfolene precursors 1 gave the cyclized products 3 with complete control of chemo- and regioselectivity. The cyclized products 3a and 5 underwent further reactions with nucleophiles and bases to give useful heterocyclic compounds. The N-tosyl group of the cyclic products could be selectively replaced by hydrogen or another substituent.

Aza-Diels-Alder reactions and synthetic applications of thio-substituted 1,3-dienes with arylsulfonyl isocyanates

The first aza-Diels-Alder reactions of arylsulfonyl isocyanates with thio-substituted 1,3-dienes via the 3-sulfolene precursors 1 gave the cyclized products 3 with complete control of regio- and chemoselectivity. The cyclized products 3a and 4 underwent further interesting reactions with nucleophiles and bases to give useful heterocyclic compounds. (C) 2000 Elsevier Science Ltd.