31739-56-7

Usage

Uses

Used in Organic Synthesis:
2-(1H-PYRROL-1-YL)BENZALDEHYDE is used as a versatile building block in organic synthesis for the construction of a wide range of biologically active molecules. Its unique structure allows for the formation of complex organic compounds that can be utilized in various applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-(1H-PYRROL-1-YL)BENZALDEHYDE is employed as a reagent in the preparation of heterocyclic compounds. These heterocyclic compounds have potential applications in drug discovery and manufacturing, contributing to the development of new therapeutic agents.
Used in Antimicrobial and Antifungal Drug Development:
2-(1H-pyrrol-1-yl)benzaldehyde has been investigated for its potential antimicrobial and antifungal properties. This makes it a valuable tool in the development of new drugs and treatments for various infectious diseases, offering a promising avenue for combating resistant strains and expanding treatment options.
Used in Drug Discovery:
2-(1H-PYRROL-1-YL)BENZALDEHYDE's role in the synthesis of heterocyclic compounds positions it as a significant player in drug discovery. The exploration of its properties and potential interactions with biological targets can lead to the identification of new pharmaceutical agents with improved efficacy and safety profiles.

InChI:InChI=1/C11H9NO/c13-9-10-5-1-2-6-11(10)12-7-3-4-8-12/h1-9H

Upstream product

• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 529-23-7 o-aminobenzaldehyde 
• 61034-86-4 2-(pyrrol-1-yl)-benzyl alcohol 
• 10333-67-2 methyl 2-(1H-pyrrol-1-yl)benzoate 
• 134-20-3 2-carbomethoxyaniline 

Downstream Products

• 323185-54-2 methyl cis-2-(1H-pyrrol-1-yl)-α-phenylcinnamate 
• 1026691-83-7 4-(2-trifluoromethyl-phenylamino)-pyrrolo[1,2-a]quinolin-5-ol 

Relevant academic research and scientific papers

NOVEL HETEROARYL COMPOUND, ENANTIOMER, DIASTEREOMER OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND ANTIVIRAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT

The present invention relates to a novel heteroaryl compound, an enantiomer, a diastereomer or a pharmaceutically acceptable salt thereof, and an antiviral composition comprising the same as an active ingredient. The novel compounds represented by formula (I) or formula (II) according to the present invention are remarkably superior in antiviral activity against an influenza virus, and furthermore, have low cytotoxicity and thus low adverse effects on a human body. Therefore, a pharmaceutical composition containing the same as an active ingredient can be effectively used for the prevention or treatment of diseases caused by an influenza virus infection.

Regioselective synthesis of diversely substituted diazoninones through a post-Ugi gold-catalyzed intramolecular hydroarylation process

A highly efficient approach for the regioselective construction of fused nine-membered rings (diazoninone framework) was developed by employing sequential Ugi and gold-catalyzed intramolecular hydroarylation reactions. The scope of this intramolecular cyc

Morita-Baylis-Hillman route to 4H-pyrrolo[1,2-a][1]benzazepine derivatives

A simple method for synthesizing substituted 4H-pyrrolo[1,2-a][1]benzazepines using acid-assisted cyclization of the Morita-Baylis-Hillman adducts of 2-(1H-pyrrol-1-yl)benzaldehydes with methyl acrylate or methyl vinyl ketone as a key step has been developed.

A facile synthesis of 9-dialkylamino-9H-pyrrolo[1,2-a]indoles via iminium salts generated from 2-(pyrrol-1-yl)benzaldehydes and secondary amine hydrochlorides in the presence of NaI/TMSCl/Et3N

The NaI/TMSCl/Et3N-mediated condensation between 2-(pyrrol-1-yl)benzaldehydes and secondary amine hydrochlorides followed by intramolecular trapping of the resulting iminium carbon by the 2-position of the pyrrole ring afforded corresponding 9-

Lewis acid catalyzed synthesis of 4-aminopyrrolo[1,2-a]quinolin-5-ol derivatives from 2-(1-pyrrolyl)benzaldehyde and isocyanides

Reaction of 2-(1-pyrrolyl)benzaldehyde with isocyanides in the presence of a catalytic amount of boron trifluoride diethyl etherate was followed by treatment with acetic anhydride in pyridine to give the corresponding O-acetyl derivatives of 4-alkyl(or ar

Polycondensed heterocycles. Part 11: Preparation and regioselective reductions of 5-phenyl-4H-pyrrolo[1,2-α][1]benzazepin-4-one

The Wadsworth-Emmons olefination between 2-(1H-pyrrol-1-yl)benzaldehyde and methyl α-(diethylphosphonyl)phenyl-acetate leads exclusively to the cis-isomer of methyl 2-(1H-pyrrol-1-yl)-α-phenylcinnamate, which, after transformation into the corresponding a

SYNTHESIS OF PYRROLOQUINOLINE AND PYRROLONAPHTHYRIDINE BY AN INTRAMOLECULAR CYCLISATION REACTION

4-methylthiopyrrolonaphthyridine and pyrroloquinoline were prepared by an intramolecular cyclisation in acidic media of 1-methylsulfinyl-1-methylthio-2-ethylene.