31739-56-7

Basic information

• Product Name: 2-(1H-PYRROL-1-YL)BENZALDEHYDE
• Synonyms: 2-(1H-PYRROL-1-YL)BENZALDEHYDE;2-pyrrol-1-ylbenzaldehyde
• CAS NO: 31739-56-7
• Molecular Formula: C₁₁H₉NO
• Molecular Weight: 171.2
• Mol File: 31739-56-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 156 °C
• Boiling Point: 312.8 °C at 760 mmHg
• Flash Point: 143 °C
• Appearance: /
• Density: 1.06 g/cm³
• Vapor Pressure: 0.000516mmHg at 25°C
• Refractive Index: 1.573
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -5.65±0.70(Predicted)
• CAS DataBase Reference: 2-(1H-PYRROL-1-YL)BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1H-PYRROL-1-YL)BENZALDEHYDE(31739-56-7)
• EPA Substance Registry System: 2-(1H-PYRROL-1-YL)BENZALDEHYDE(31739-56-7)

Safety Data

• Hazardous Substances Data: 31739-56-7(Hazardous Substances Data)

Usage

Description

2-(1H-PYRROL-1-YL)BENZALDEHYDE, also known as pyrrole-2-carboxaldehyde, is a chemical compound with the formula C11H9NO. It features a benzene ring with a 2-pyrrole substituent and an aldehyde functional group. 2-(1H-PYRROL-1-YL)BENZALDEHYDE is recognized for its versatility in organic synthesis and pharmaceutical research, serving as a key building block for the creation of various biologically active molecules.

Uses

Used in Organic Synthesis:
2-(1H-PYRROL-1-YL)BENZALDEHYDE is used as a versatile building block in organic synthesis for the construction of a wide range of biologically active molecules. Its unique structure allows for the formation of complex organic compounds that can be utilized in various applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-(1H-PYRROL-1-YL)BENZALDEHYDE is employed as a reagent in the preparation of heterocyclic compounds. These heterocyclic compounds have potential applications in drug discovery and manufacturing, contributing to the development of new therapeutic agents.
Used in Antimicrobial and Antifungal Drug Development:
2-(1H-pyrrol-1-yl)benzaldehyde has been investigated for its potential antimicrobial and antifungal properties. This makes it a valuable tool in the development of new drugs and treatments for various infectious diseases, offering a promising avenue for combating resistant strains and expanding treatment options.
Used in Drug Discovery:
2-(1H-PYRROL-1-YL)BENZALDEHYDE's role in the synthesis of heterocyclic compounds positions it as a significant player in drug discovery. The exploration of its properties and potential interactions with biological targets can lead to the identification of new pharmaceutical agents with improved efficacy and safety profiles.

InChI:InChI=1/C11H9NO/c13-9-10-5-1-2-6-11(10)12-7-3-4-8-12/h1-9H

Upstream product

• 10333-67-2 methyl 2-(1H-pyrrol-1-yl)benzoate 
• 134-20-3 2-carbomethoxyaniline 
• 61034-86-4 2-(pyrrol-1-yl)-benzyl alcohol 
• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 529-23-7 o-aminobenzaldehyde 

Downstream Products

• 1171107-32-6 methyl 2-[1-hydroxy-1-(2-(1H-pyrrol-1-yl)phenyl)methyl]propenoate 
• 1604835-43-9 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(tert-butylamino)-2-oxoethyl}-N-(4-methoxybenzyl)but-2-ynamide 
• 1604835-44-0 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(cyclohexylamino)-2-oxoethyl}-N-(4-methoxybenzyl)but-2-ynamide 
• 1604835-45-1 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(butylamino)-2-oxoethyl}-N-(4-methoxybenzyl)but-2-ynamide 
• 1604835-49-5 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(p-tolylamino)-2-oxoethyl}-N-(4-methoxybenzyl)but-2-ynamide 
• 1604835-53-1 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(tert-butylamino)-2-oxoethyl}-N-(4-methoxybenzyl)-3-phenylpropiolamide 
• 1604835-55-3 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(tert-butylamino)-2-oxoethyl}-N-(4-methoxybenzyl)propiolamide 
• 1604835-46-2 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(tert-butylamino)-2-oxoethyl}-N-(3,4-dimethoxybenzyl)but-2-ynamide 
• 1604835-47-3 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(cyclohexylamino)-2-oxoethyl}-N-(benzo[d][1,3]dioxol-5-ylmethyl)but-2-ynamide 
• 1604835-48-4 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(tert-butylamino)-2-oxoethyl}-N-(benzo[d][1,3]dioxol-5-ylmethyl)pent-2-ynamide 
• 1604835-56-4 N-{1-[2-(1H-pyrrol-1-yl)phenyl]-2-(tert-butylamino)-2-oxoethyl}-N-benzylpropiolamide 
• 1604835-29-1 (Z)-N-(tert-butyl)-6-(4-methoxybenzyl)-9-methyl-7-oxo-6,7-dihydro-5H-benzo[b]pyrrolo[2,1-i][1,5]diazonine-5-carboxamide 
• 1604835-32-6 (Z)-N-butyl-6-(4-methoxybenzyl)-9-methyl-7-oxo-6,7-dihydro-5Hbenzo[b]pyrrolo[2,1-i][1,5]diazonine-5-carboxamide 
• 1604835-33-7 (Z)-6-(benzo[d][1,3]dioxol-5-ylmethyl)-N-cyclohexyl-9-methyl-7-oxo-6,7-dihydro-5H-benzo[b]pyrrolo[2,1-i][1,5]diazonine-5-carboxamide 

Relevant articles and documents

NOVEL HETEROARYL COMPOUND, ENANTIOMER, DIASTEREOMER OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND ANTIVIRAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT

The present invention relates to a novel heteroaryl compound, an enantiomer, a diastereomer or a pharmaceutically acceptable salt thereof, and an antiviral composition comprising the same as an active ingredient. The novel compounds represented by formula (I) or formula (II) according to the present invention are remarkably superior in antiviral activity against an influenza virus, and furthermore, have low cytotoxicity and thus low adverse effects on a human body. Therefore, a pharmaceutical composition containing the same as an active ingredient can be effectively used for the prevention or treatment of diseases caused by an influenza virus infection.

Morita-Baylis-Hillman route to 4H-pyrrolo[1,2-a][1]benzazepine derivatives

A simple method for synthesizing substituted 4H-pyrrolo[1,2-a][1]benzazepines using acid-assisted cyclization of the Morita-Baylis-Hillman adducts of 2-(1H-pyrrol-1-yl)benzaldehydes with methyl acrylate or methyl vinyl ketone as a key step has been developed.

Lewis acid catalyzed synthesis of 4-aminopyrrolo[1,2-a]quinolin-5-ol derivatives from 2-(1-pyrrolyl)benzaldehyde and isocyanides

Reaction of 2-(1-pyrrolyl)benzaldehyde with isocyanides in the presence of a catalytic amount of boron trifluoride diethyl etherate was followed by treatment with acetic anhydride in pyridine to give the corresponding O-acetyl derivatives of 4-alkyl(or ar