31758-87-9

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 78-84-2 isobutyraldehyde 
• 6651-34-9 2-methyl-1-(trimethylsilyloxy)-1-propene 

Downstream Products

• 515174-37-5 4-(4-chloro-phenyl)-5,5-dimethyl-[1,3,2]dioxaphosphinane 2-oxide 
• 98674-88-5 4-(4-chlorophenyl)-5,5-dimethyl-2-hydroxy-1,3,2-dioxaphosphorinane 2-oxide 

Relevant academic research and scientific papers

A novel synthesis of 2,5-disubstituted 1,3,4-oxadiazolines by the regioselective cyclization of 1,4-disubstituted thiosemicarbazides

A novel and efficient route for the regioselective synthesis of 5-aryl-2-[(4-aryl-2-oxo-1,3,2-dioxaphosphinan-2-yl)imino]-2,3-dihydro-1,3, 4-oxadiazoles in high yield and purity by the desulfurization and cyclization of 1-benzoyl-4-[(4-aryl-2-oxo-1,3,2-di

Optical enrichment in enzyme-catalyzed resolution of 1-aryl-2,2-dimethyl-1,3-propanediols

Novozym 435 efficiently catalyzed the chemo-, regio-, and enantioselective transesterification of 1-aryl-2,2-dimethyl-1,3-propanediols in different organic solvents with vinyl acetate as the acetyl donor at room temperature. This enzyme-catalyzed chemical

Asymmetric cyclic phosphorothonamides containing substituted pyridine

In order to find high-acitivity and low-toxicity pesticidal lead compounds, a type of novel, asymmetric cyclic phosphorothonamides containing substituted pyridine were synthesized via the condensation reactions of 2-chloro-4- substitutedphenyl-5,5-dimethy

Synthesis and biological activity of cis 2-(6-chloropyridine-3-yl) methylamino-4-substitutedphenyl-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxides

A series of novel, asymmetric-cyclic phosphoramides containing substituted pyridine were synthesized via the condensation reactions of trans 2-chloro-4-substitutedphenyl-5, 5-dimethyl-1,3,2-dioxaphosphinane 2-oxide with 2-chloro-5-aminomethylpyridine or 3

Synthesis and fugicidal activities of 2-silatranyl propylamino-4-substitued phenyl(hydrogen)-5,5-dimethyl-1,3,2-dioxaphosphinanes-2-oxides (sulfides)

Phosphoryl-aminopropyl-silatranes 4 were synthesized by nucleophilic reactions of 2-Cl-1,3,2- dioxaphosphinanes 2 with α-aminopropyl-silatrane 3, which was obtained by the cyclization reaction of triethanolamine and γ-aminopropyltriethoxysilane. The structures of the products were characterized by 1H NMR, 31P NMR, IR, MS, and elemental analyses. The target compounds 4 exhibited fungicidal activity. Copyright Taylor & Francis Inc.

Lithium acetate-catalyzed crossed aldol reaction between aldehydes and trimethylsilyl enolates generated from other aldehydes

Crossed aldol reaction between aromatic aldehydes having an electron-withdrawing group and trimethylsilyl enolates generated from several aldehydes proceeded smoothly in dry or water-containing DMF in the presence of a catalytic amount of a Lewis base such as lithium acetate or lithium benzoate. Successive reduction of the produced aldehydes with sodium borohydride (NaBH4) afforded the corresponding 1,3-diols in good to high yields in one-pot. Copyright

The Design of Resolving Agents. Chiral Cyclic Phosphoric Acids

A systematic investigation has been started with the twofold purpose of synthesizing efficient resolving agents and of gaining an insight into the factors that contribute to successful resolutions.We report on the synthesis, resolution, and application of a number of chiral cyclic phosphoric acids.Among these acids, 4-(2-chlorophenyl)-5,5-dimethyl-2-hydroxy-1,3,2-dioxaphosphorinane 2-oxide (7A) is an efficient resolving agent, being useful for the resolution of amines and amino acids.Acid chloride 20 is a useful reagent for the determination of the ee of chiral amines.The absolute configuration of (-)-7A was determined through an X-ray structure determination of its salt with (-)-(p-hydroxyphenyl)glycine.