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1-Bromo-3-methoxy-2-methylbenzene, also known as o-bromoanisole or 3-bromoanisole, is an organic compound with the formula C8H9BrO. It belongs to the family of bromobenzenes and can be classified as a bromoanisole. This light yellow to amber liquid has a molecular weight of 201.06 g/mol and is relatively nonpolar, making it insoluble in water but soluble in organic solvents. Due to its potential harmful effects if swallowed, inhaled, or comes in contact with skin, careful handling and storage are required.

31804-36-1

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31804-36-1 Usage

Uses

Used in Organic Synthesis:
1-Bromo-3-methoxy-2-methylbenzene is used as a reagent in laboratory settings for organic synthesis, particularly in the preparation of various organic compounds.
Used in Pharmaceutical Industry:
1-Bromo-3-methoxy-2-methylbenzene is used as an intermediate in the manufacturing of pharmaceuticals, contributing to the development of new drugs and medicines.
Used in Dye Manufacturing:
1-BROMO-3-METHOXY-2-METHYLBENZENE is also utilized as a key component in the production of dyes, playing a significant role in the coloration and properties of various dyes used in different industries.
Used in Other Organic Compounds Production:
1-Bromo-3-methoxy-2-methylbenzene serves as a building block in the synthesis of other organic compounds, expanding its applications across various chemical and industrial processes.

Check Digit Verification of cas no

The CAS Registry Mumber 31804-36-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,8,0 and 4 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 31804-36:
(7*3)+(6*1)+(5*8)+(4*0)+(3*4)+(2*3)+(1*6)=91
91 % 10 = 1
So 31804-36-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H9BrO/c1-6-7(9)4-3-5-8(6)10-2/h3-5H,1-2H3

31804-36-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-bromo-3-methoxy-2-methylbenzene

1.2 Other means of identification

Product number -
Other names 2-methyl-3-bromoanisole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:31804-36-1 SDS

31804-36-1Relevant articles and documents

Divergent Enantioselective Synthesis of (Nor)illudalane Sesquiterpenes via Pd0-Catalyzed Asymmetric C(sp3)-H Activation

Melot, Romain,Craveiro, Marcus V.,Bürgi, Thomas,Baudoin, Olivier

, p. 812 - 815 (2019/01/21)

A divergent enantioselective synthesis of (nor)illudalane sesquiterpenes was designed by using a Pd0-catalyzed asymmetric C(sp3)-H arylation as a key step to control the isolated, highly symmetric quaternary stereocenter of the targe

Total Synthesis of (Nor)illudalane Sesquiterpenes Based on a C(sp3)-H Activation Strategy

Melot, Romain,Craveiro, Marcus V.,Baudoin, Olivier

, p. 12933 - 12945 (2019/08/20)

Three (nor)illudalane sesquiterpenes were synthesized from a common intermediate in racemic and enantioenriched forms using Pd0-catalyzed C(sp3)-H arylation as a key step. The configuration of the isolated, highly symmetric quaternar

Axially Chiral Dibenzazepinones by a Palladium(0)-Catalyzed Atropo-enantioselective C?H Arylation

Newton, Christopher G.,Braconi, Elena,Kuziola, Jennifer,Wodrich, Matthew D.,Cramer, Nicolai

, p. 11040 - 11044 (2018/07/31)

Atropo-enantioselective C?H functionalization reactions are largely limited to the dynamic kinetic resolution of biaryl substrates through the introduction of steric bulk proximal to the axis of chirality. Reported herein is a highly atropo-enantioselective palladium(0)-catalyzed methodology that forges the axis of chirality during the C?H functionalization process, enabling the synthesis of axially chiral dibenzazepinones. Computational investigations support experimentally determined racemization barriers, while also indicating C?H functionalization proceeds by an enantio-determining CMD to yield configurationally stable eight-membered palladacycles.

Propionic Acid Derivatives and Methods of Use Thereof

-

, (2018/11/21)

Provided herein are compounds and pharmaceutical compositions of formula I where R1, R2, R3, R4, R5 and R6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomers of these compounds. In addition methods are provided for inhibiting the binding of an integrin to treat various pathophysiological conditions.

NOVEL 2-OXO-6,7-DIHYDROBENZO[A]QUINOLIZINE-3-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

-

Page/Page column 53, (2016/09/22)

The invention provides novel compounds having the general formula (I), wherein R1, R2, R3, R4, R5 and Ar are as described herein, compositions including compounds and methods of using the compounds.

NOVEL NEUROKININ 1 RECEPTOR ANTAGONIST COMPOUNDS II

-

Page/Page column 108, (2015/03/13)

The invention relates novel NK1 receptor antagonists represented in formula A, wherein R1 and R2 independently are selected from the group consisting of (C1-4)alkyl, (C1-4)haloalkyl, (C1-4)alkoxy, CD

NRF2 REGULATORS

-

Page/Page column 201, (2015/07/07)

The present invention relates to bis aryl analogs, pharmaceutical compositions containing them and their use as Nrf2 regulators.

DERIVATIVES OF 1-PHENYL-1,5-DIHYDRO-BENZO[B] [1.4]DIAZEPINE-2.4-DIONE AS INHIBITORS OF HIV REPLICATION

-

, (2011/09/19)

Compounds of formula (I) wherein m, R1, R2, R3, X and Y are defined herein, are useful as inhibitors of HIV replication.

Total synthesis of new lipocarbazoles isolated from the actinomycete tsukamurella pseudospumae acta 1857

H?nchen, Anne,Süssmuth, Roderich D.

body text, p. 2483 - 2486 (2010/01/07)

New lipocarbazoles were synthesized by a sequence of three palladium-mediated coupling reactions and an improved protecting group strategy.

BENZOXAZOCINES AND THEIR THERAPEUTIC USE AS MONOAMINE REUPTAKE INHIBITORS

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Page/Page column 27, (2010/02/14)

Compounds having therapeutic utility are of general formula (1) wherein R, is H, C 1-C6 alkyl optionally substituted with F or C3-C6 cycloalkyl or C2-C4 alkenyl; A is O, CH2 or S(O)n where n is 0-2; one of W, X, Y and Z is N, CH or CR3 and the others are CH; R2 is C5-C6 heteroaryl, C5-C10 cycloalkyl or cycloalkenyl optionally containing one or more heteroatoms selected from O, N and S(O)n where n is 0-2, and optionally substituted with R3; or a phenyl group optionally substituted in one or more positions with one or more substituents independently selected from halogen, CN, CF3, C1-C6 alkyl and OR1, or the phenyl group is fused to a five or six membered ring which may be carbocyclic, heterocyclic (containing 1-2 heteroatoms selected from O, N and S), aromatic or heteroaromatic (containing 1-2 heteroatoms selected from O and N); R3 is selected from halogen; CF3; CN; OR5; SO2N(R5)2; COR5; CO2R5; CON(R5)2; NR1,COR4; NR1SO2R4; NR1CO2R4; NR1,CON(R5)2; OC1-C6 alkyl substituted with R3; C1-C6 alkyl optionally substituted with unsubstituted R3; C3-C6 cycloalkyl optionally substituted with unsubstituted R3; C2-Cs alkenyl optionally substituted with unsubstituted R3; C2-Cs alkynyl optionally substituted with unsubstituted R3; aryl optionally substituted with unsubstituted R3; and five or six membered aromatic heterocycles containing 1-4 heteroatoms selected from N and O; R4 is C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C6 cycloalkyl, aryl and heteroaryl; and R5 is H, C1-C6 alkyl; C2-C6 alkenyl, C2-C6 alkynyl, C3-C6 cycloalkyl, aryl or heteroaryl and is the same as or different to another R5; or a pharmaceutically acceptable salt thereof.

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