31827-21-1Relevant academic research and scientific papers
Heterocycles from Nitrile Oxides. 3. 1,2,4-Oxadiazol-5(4H)-ones
Hussein, Ahmad Q.
, p. 127 - 128 (2007/10/02)
The reaction of nitrile oxides with potassium cyanate gives 3-aryl-1,2,4-oxadiazol-5(4H)-ones (5).These heterocycles are also obtained by cyclization of the corresponding O-carbethoxyamidoximes (7) with sodium ethoxide.
CYCLIZATION OF C- AND O-ACYL DERIVATIVES OF p-TOLUAMIDE O-ACETOACETYLOXIME
Kawashima, Etsuko,Ando, Yuko,Tabei, Katsumi,Miyamae, Hiroshi
, p. 1015 - 1028 (2007/10/02)
Reaction of p-toluamide O-acetoacetyloxime (1) with acyl chloride (2) in the presence of basic catalyst gave the corresponding O- and C-acyl derivatives (3 and 4).Cyclization of 3 afforded 5-(2-acyloxypropenyl)-3-(p-tolyl)-1,2,4-oxadiazole derivatives (6)
