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2,4,6-Trichlorophenyl chlorothionoformate, with the chemical formula C7H2Cl3FO, is a white crystalline solid that serves as an intermediate in the synthesis of various organic compounds. It is a powerful acylating agent, capable of introducing the trichloromethylthio group into organic molecules. Additionally, it is a potent inhibitor of acetylcholinesterase, an enzyme involved in the breakdown of the neurotransmitter acetylcholine in the nervous system. Due to its toxic and potentially harmful properties, it requires proper handling and safety precautions.

31836-18-7

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31836-18-7 Usage

Uses

Used in Organic Synthesis:
2,4,6-Trichlorophenyl chlorothionoformate is used as a reagent in organic synthesis for its acylating properties, allowing the introduction of the trichloromethylthio group into organic molecules. This enhances the reactivity and functional groups of the target compounds, making it a valuable tool in the synthesis of various organic compounds.
Used in Agrochemicals:
In the agrochemical industry, 2,4,6-Trichlorophenyl chlorothionoformate is used as an intermediate in the synthesis of various agrochemicals. Its ability to introduce the trichloromethylthio group into organic molecules contributes to the development of effective pesticides and other agricultural chemicals.
Used in Pharmaceuticals:
2,4,6-Trichlorophenyl chlorothionoformate is also used in the pharmaceutical industry as an intermediate in the synthesis of various pharmaceuticals. Its acylating properties and ability to modify the functional groups of organic molecules make it a useful component in the development of new drugs and therapeutic agents.
Used as an Acetylcholinesterase Inhibitor:
Due to its potent inhibitory effect on acetylcholinesterase, 2,4,6-Trichlorophenyl chlorothionoformate has potential applications in the development of drugs targeting neurological disorders. By inhibiting the enzyme responsible for breaking down acetylcholine, it may help in the treatment of conditions such as Alzheimer's disease and other cognitive impairments.
However, it is important to note that due to the toxic and potentially harmful properties of 2,4,6-Trichlorophenyl chlorothionoformate, its use in pharmaceutical applications requires careful consideration and extensive research to ensure safety and efficacy.

Check Digit Verification of cas no

The CAS Registry Mumber 31836-18-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,8,3 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 31836-18:
(7*3)+(6*1)+(5*8)+(4*3)+(3*6)+(2*1)+(1*8)=107
107 % 10 = 7
So 31836-18-7 is a valid CAS Registry Number.

31836-18-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name O-(2,4,6-trichlorophenyl) chloromethanethioate

1.2 Other means of identification

Product number -
Other names 2,4,6-Trichlorophenyl chlorothionoformate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:31836-18-7 SDS

31836-18-7Relevant academic research and scientific papers

The Invention of Radical Reactions. Part XXI. Simple Methods for the Radical Deoxygenation of Primary Alcohols.

Barton, Derek H. R.,Blundell, Paul,Dorchak, Joseph,Jang, Doo Ok,Jaszberenyi, Joseph Cs.

, p. 8969 - 8984 (2007/10/02)

Novel radical-chain deoxygenations of primary alcohols are described.The alcohols are acylated with the reagents pentafluorophenyl chlorothionoformate, 2,4,6-trichlorophenyl chlorothionoformate and 4-fluorophenyl chlorothionoformate and the intermediate thionocarbonates are deoxygenated with tributyltin hydride, triphenylsilane, diphenylsilane or phenylsilane in high-yielding reactions.Key Words: Thionocarbonates, Tributyltin hydride, Triphenylsilane, Diphenylsilane, Phenylsilane, Radical deoxygenations.

IMPROVED METHODS FOR THE RADICAL DEOXYGENATION OF SECONDARY ALCOHOLS

Barton, Derek H. R.,Jaszberenyi, Joseph Cs.

, p. 2619 - 2622 (2007/10/02)

The reaction of Barton and McCombie has been improved by the use of the new reagents 2,4,6-trichlorophenoxythiocarbonyl chloride and its congener pentafluorophenoxythiocarbonyl chloride.Deoxygenations with these derivatives of 1,2:5,6-diacetoneglucofurano

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