31860-66-9Relevant academic research and scientific papers
TBAF-Catalysed silver oxide-mediated cross-coupling of functional trimethysilylpyridines: Access to arylpyridines and bihetaryl compounds
Louerat, Frederic,Tye, Heather,Napier, Spencer,Garrigou, Michael,Whittaker, Mark,Gros, Philippe C.
scheme or table, p. 1768 - 1773 (2011/04/26)
The concomitant use of silver oxide and catalytic amount of TBAF allowed the efficient and chemoselective coupling of readily available 4-chloro- and 4-methyl-2-trimethyl-silyl-pyridines with heteroaromatic and aromatic halides. Based on control experiments, a mechanism involving the formation of a pyridylsilver intermediate and TBAF recycling is postulated.
