3187-51-7 Usage
Uses
Used in Pharmaceutical Industry:
7-Methoxy-chroman-3-carboxylic acid is used as a building block for the synthesis of new compounds with potential pharmaceutical properties, due to its versatile structure and the possibility of it having antioxidant and anti-inflammatory effects.
Used in Organic Synthesis:
7-Methoxy-chroman-3-carboxylic acid is used as a key intermediate in organic synthesis for creating a variety of chemical compounds, leveraging its unique chroman ring structure and functional groups.
Used in Medicinal Chemistry:
7-Methoxy-chroman-3-carboxylic acid is utilized in medicinal chemistry as a starting material for the development of novel drug candidates, given its potential to contribute to the creation of therapeutic agents with beneficial health effects.
Check Digit Verification of cas no
The CAS Registry Mumber 3187-51-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,8 and 7 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3187-51:
(6*3)+(5*1)+(4*8)+(3*7)+(2*5)+(1*1)=87
87 % 10 = 7
So 3187-51-7 is a valid CAS Registry Number.
3187-51-7Relevant academic research and scientific papers
The development of benzimidazoles as selective rho kinase inhibitors
Sessions, E. Hampton,Smolinski, Michael,Wang, Bo,Frackowiak, Bozena,Chowdhury, Sarwat,Yin, Yan,Chen, Yen Ting,Ruiz, Claudia,Lin, Li,Pocas, Jennifer,Schr?ter, Thomas,Cameron, Michael D.,LoGrasso, Philip,Feng, Yangbo,Bannister, Thomas D.
scheme or table, p. 1939 - 1943 (2010/09/03)
Rho Kinase (ROCK) is a serine/threonine kinase whose inhibition could prove beneficial in numerous therapeutic areas. We have developed a promising class of ATP-competitive inhibitors based upon a benzimidazole scaffold, which show excellent potency toward ROCK (IC50 10 nM). This report details the optimization of selectivity for ROCK over other related kinases such as Protein kinase A (PKA).
