318949-09-6

Basic information

• Product Name: (2R,3R)-2,3-Bis-benzoyloxy-succinic acid (2R,3S)-5,7-bis-benzyloxy-2-(3,4-bis-benzyloxy-phenyl)-chroman-3-yl ester methyl ester
• Synonyms: (2R,3R)-2,3-Bis-benzoyloxy-succinic acid (2R,3S)-5,7-bis-benzyloxy-2-(3,4-bis-benzyloxy-phenyl)-chroman-3-yl ester methyl ester
• CAS NO: 318949-09-6
• Molecular Weight: 1005.09
• Mol File: 318949-09-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R)-2,3-Bis-benzoyloxy-succinic acid (2R,3S)-5,7-bis-benzyloxy-2-(3,4-bis-benzyloxy-phenyl)-chroman-3-yl ester methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-2,3-Bis-benzoyloxy-succinic acid (2R,3S)-5,7-bis-benzyloxy-2-(3,4-bis-benzyloxy-phenyl)-chroman-3-yl ester methyl ester(318949-09-6)
• EPA Substance Registry System: (2R,3R)-2,3-Bis-benzoyloxy-succinic acid (2R,3S)-5,7-bis-benzyloxy-2-(3,4-bis-benzyloxy-phenyl)-chroman-3-yl ester methyl ester(318949-09-6)

Safety Data

• Hazardous Substances Data: 318949-09-6(Hazardous Substances Data)

Upstream product

• 2743-38-6 O,O'-dibenzoyl-L-tartaric acid 
• 115061-55-7 (2R,3R)-2,3-dibenzoyloxy-3-methoxycarbonylpropanoic acid 

Downstream Products

• 154-23-4 catechin 
• 20728-73-8 5,7,3',4'-tetra-O-benzyl-(+)-catechin 

Relevant articles and documents

Methods in synthesis of flavonoids. Part 2: High yield access to both enantiomers of catechin

Resolution of racemic synthetic tetra-O-benzylcatechin 2 is described, through the formation of esters S and 6 derived from dibenzoyl-L-tartaric acid. The diastereoisomer of the natural series 6 was separated by crystallization, the other one being an oil. This process allowed us to prepare enantiomerically pure (+)-catechin 8 in high yield. The pure isomer in the ent-series 9 could be obtained, following the same scheme of reactions. (C) 2000 Elsevier Science Ltd.