318993-95-2Relevant academic research and scientific papers
A pinene-based chiral auxiliary for α-alkylation and aldol reactions: An unexpected effect of the base on the stereoselectivity
Pinheiro, Sergio,Goncalves, Clara B.S.S.,De Lima, Marcelo B.,De Farias, Florence M.C.
, p. 3495 - 3502 (2000)
While the use of LDA as the base in the kinetic deprotonation step of the pinene-based ester 3 led to moderate diastereoselectivities in α-alkylation and aldol reactions, the use of LICA and LTMP resulted in a reduction in the anti/syn ratios and π-facial selectivities. Copyright (C) 2000 Elsevier Science Ltd.
