319-04-0

Basic information

• Product Name: Naphthalene, 7-broMo-1-fluoro-
• Synonyms: Naphthalene, 7-broMo-1-fluoro-;7-Bromo-1-fluoro-naphthalene
• CAS NO: 319-04-0
• Molecular Formula: C10H6BrF
• Molecular Weight: 225.0570432
• Mol File: 319-04-0.mol

Chemical Properties

• Boiling Point: 286.6°Cat760mmHg
• Flash Point: 130.8°C
• Appearance: /
• Density: 1.563g/cm³
• Vapor Pressure: 0.00451mmHg at 25°C
• Refractive Index: 1.638
• CAS DataBase Reference: Naphthalene, 7-broMo-1-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Naphthalene, 7-broMo-1-fluoro-(319-04-0)
• EPA Substance Registry System: Naphthalene, 7-broMo-1-fluoro-(319-04-0)

Safety Data

• Hazardous Substances Data: 319-04-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
Naphthalene, 7-bromo-1-fluorois utilized as a starting material in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure allows for the development of new compounds with specific therapeutic or pesticidal properties.
Used in Organic Synthesis:
Naphthalene, 7-broMo-1-fluoroserves as a reagent in organic synthesis, enabling the creation of a wide range of organic compounds with diverse applications. Its presence can influence the reactivity and selectivity of chemical reactions, leading to the formation of desired products.
Used in Materials Science:
Naphthalene, 7-bromo-1-fluorohas potential applications in the field of materials science, particularly in the development of new organic semiconductors and electronic devices. Its electronic properties, such as its ability to accept or donate electrons, make it a promising candidate for use in organic solar cells, transistors, and other electronic components.

InChI:InChI=1/C10H6BrF/c11-8-5-4-7-2-1-3-10(12)9(7)6-8/h1-6H

Upstream product

• 137466-05-8 7-Bromo-1-naphthyldiazonium tetrafluoroborate 
• 108-86-1 bromobenzene 
• 32281-97-3 7-bromo-3,4-dihydro-2H-naphthalen-1-one 
• 35656-89-4 4-(4-bromophenyl)butanoic acid 
• 6340-79-0 4-oxo-4-(4-bromophenyl)butanoic acid 
• 137466-04-7 7-Bromo-1-naphthylamine hydrochloride 
• 877263-91-7 7-bromo-N-hydroxy-3,4-dihydronaphthalen-1(2H)-imine 
• 51934-39-5 7-bromo-1-naphthalenecarboxylic acid 
• 33295-35-1 2-bromo-8-methylnaphthalene 
• 35943-87-4 7-bromo-1-methyl-3,4-dihydronaphthalene 
• 136924-78-2 1-amino-7-bromonaphthalene 

Downstream Products

• 2965-43-7 2-(8-Fluor-naphthoyl)-benzoesaeure 

Relevant articles and documents

SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES

The invention relates to substituted dihydropyrazolo pyrazine carboxamide derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and diabetes, and also urogenital and ophthalmic disorders.

Substituted imidazol-pyridazine derivatives

The present invention relates to compounds of formula wherein A is an unsubstituted or substituted cyclic group; and R is hydrogen or lower alkyl; or a pharmaceutically acceptable acid addition salt thereof. These compounds are NMDA NR-2B receptor subtype specific blockers and are useful in the treatment of neurodegeneration, depression and pain.

Nuclear Spin-Spin Coupling via Nonbonded Interactions. 7. Effects of Molecular Structure on N-F Coupling

To test wether the recently discovered phenomenon of through-space nuclear spin-spin coupling between intramolecularly crowded 15N and 19F nuclei shows the same sort of striking dependence on molecular structure as the long-known phenomenon of through-space nuclear spin-spin coupling between pairs of intramolecularly crowded 19F nuclei, several 15N-enriched oximes and some simple derivatives thereof were synthesized and their JNF values were determined by 19F NMR spectroscopy.The experimental JNF values ranged from 8.6 to 43.5 Hz.The molecular structures of these compounds were determined by single-crystal X-ray diffraction.The observed dependence of the 15N-19F coupling constants on molecular structure was qualitatively consistent with the predictions of the lone-pair orbital overlap theory that was developed earlier to account for through-space coupling involving fluorine nuclei.