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1H-Indole-2,3-dione, 6-fluoro-, 3-oxime is a chemical compound with the molecular formula C8H4FNO3. It is a derivative of isatin, an organic compound that is a key intermediate in the synthesis of various indole-containing natural products and pharmaceuticals. The 6-fluoro substitution in 1H-Indole-2,3-dione, 6-fluoro-, 3-oxime introduces a fluorine atom at the 6-position of the indole ring, which can significantly alter the chemical and biological properties of the molecule. The 3-oxime functional group is present at the 3-position, which is a nitrogen-oxygen double bond that can participate in various chemical reactions. 1H-Indole-2,3-dione, 6-fluoro-, 3-oxime is of interest in medicinal chemistry due to its potential applications in the development of new drugs, particularly those targeting the central nervous system. Its unique structure allows for exploration of its binding properties and potential therapeutic effects, making it a valuable compound for further research and development in the pharmaceutical industry.

319-67-5

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319-67-5 Usage

Molecular structure

1H-Indole-2,3-dione, 6-fluoro-, 3-oxime is a synthetic chemical compound derived from indole-2,3-dione with a fluorine atom at the 6 position and an oxime group at the 3 position.

Molecular weight

193.16 g/mol

Appearance

It is not mentioned in the material provided.

Physical properties

It is not mentioned in the material provided.

Chemical properties

+ The oxime group present in 1H-Indole-2,3-dione, 6-fluoro-, 3-oxime gives it the potential to undergo various chemical reactions.
+ It can act as a building block for the synthesis of biologically active molecules.
+ It is a versatile intermediate for the production of pharmaceuticals and agrochemicals.

Applications

1H-Indole-2,3-dione, 6-fluoro-, 3-oxime has potential applications in the field of medicinal chemistry and drug development. Further research and development may lead to the discovery of novel drugs or other valuable compounds with important commercial and industrial applications.

Check Digit Verification of cas no

The CAS Registry Mumber 319-67-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,1 and 9 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 319-67:
(5*3)+(4*1)+(3*9)+(2*6)+(1*7)=65
65 % 10 = 5
So 319-67-5 is a valid CAS Registry Number.

319-67-5Downstream Products

319-67-5Relevant academic research and scientific papers

Synthesis of isatin 3-oximes from 2-nitroacetanilides

Kearney,Harris,Jackson,Joule

, p. 769 - 772 (2007/10/02)

2-Nitroacetanilides, prepared by alkaline hydrolysis of 1-arylamino-1-methylthio-2-nitroethenes, are converted into isatin (1H-indole-2,3-dione) 3-oximes by treatment with concentrated sulfuric acid or trifluoromethanesulfonic acid at room temperature.

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