319-82-4

Usage

InChI:InChI=1/C8H4F10/c9-3-1-2-5(11,7(13,14)15)4(10)6(3,12)8(16,17)18/h1-4H

Upstream product

• 402-31-3 1,3-bis(trifluoromethyl)benzene 
• 392-56-3 Hexafluorobenzene 

Downstream Products

• 2010-55-1 2,3,5-Trifluor-4,6-Bistrifluormethyltoluol 
• 2176-83-2 4,6-Bis-trifluormethyl-1-methoxy-trifluor-benzol 
• 2010-56-2 1,3-Dimethoxy-4,6-bis-trifluormethyl-difluor-benzol 
• 1551-39-9 2,4,5,6-tetrafluoroisophthalic acid 
• 2010-75-5 2,4-bis(trifluoromethyl)-3,5,6-trifluorobenzenethiol 
• 2280-52-6 2,4-bis(trifluoromethyl)-trifluorophenylhydrazine 
• 2010-74-4 1,3-dihydrazino-4,6-bis(trifluoromethyl)-difluorobenzene 
• 63812-16-8 piperidinium fluoride 
• 2176-82-1 1,3-bis(trifluoromethyl)-2,4,5-trifluorobenzene 
• 136264-68-1 m-(chlorodifluoromethyl)heptafluorotoluene 
• 136264-69-2 m-(trichloromethyl)heptafluorotoluene 
• 136264-71-6 1,3-bis(trichloromethyl)-2,4,5,6-tetrafluorobenzene 
• 161039-05-0 N-(pentafluorophenyl)-2,4,5,6-tetrafluoro-3-trichloromethylbenzimidoyl chloride 
• 2870-66-8 1,3-bis(trifluoromethyl)-3,5,6-trifluorophenol 

Relevant academic research and scientific papers

Selective mono-and diamination of polyfluorinated benzenes and pyridines with liquid ammonia

Amination of pentafluoropyridine, 2,3,5,6-tetrafluoropyridine, 4-chlorotetrafluoropyridine, 3,5-dichlorotrifluoropyridine, octafluorotoluene, α,α,α,2,3,5,6-heptafluorotoluene, decafluoro-m-xylene, decafluorobiphenyl, hexafluorobenzene, and pentafluorobenzene with liquid ammonia was investigated. Bis-aminodefluorination temperatures for the majority of substrates were shown to exceed significantly the corresponding temperatures of monoaminodefluorination. The optimal conditions for selective preparation of mono-and diaminopolyfluoro(het)arenes were elucidated. An efficient method for isolation of particular polyfluorophenylenediamines from product mixtures formed in nonselective reactions of pentafluorobenzene and hexafluorobenzene with aqueous ammonia based on complexation with a crown ether is proposed.

Skeletal transformations and fluorination of perfluoroalkylbenzenes in reactions with antimony pentafluoride

Reaction of octafluorotoluene and perfluoro-m-xylene with tetrafluoroethylene in the presence of SbF5 yielded perfluorinated propyl-and 1,3-dipropylbenzene, and propyltoluene. The perfluoropropyl group of these compounds under the action of SbF5 at 200°C is transformed into perfluoroisopropyl or trifluoromethyl group. Polyfluoroalkylbenzenes in SbF5 medium undergo fluorinationb to afford perfluoro1-alkylcyclohexenes.

FLUORINATIONS WITH COMPLEX METAL FLUORIDES. PART 9. FLUORINATIONS OF TOLUENE AND XYLENE DERIVATIVES BY MEANS OF CAESIUM TETRAFLUOROCOBALTATE(III)

Benzotrifluoride at 320 deg C afforded some m-fluorobenzotrifluoride and octafluorotoluene (III), together with perfluoromethylcyclohexane (I), and also traces of 2H-heptafluorotoluene and 1-trifluoromethylnonafluorocyclohex-1-ene.Toluene itself gave (difluoromethyl)benzene, fluoro- and difluoro-methylpentafluorobenzene, difluoromethylundecafluorocyclohexane and (I); also traces of di- and tri-fluoromethylnonafluorocyclohex-1-ene: no benzotrifluoride or (III) were detected. 1,3-Bis(trifluoromethyl)benzene at 420 deg C gave 4,5,6-trifluoro-1,3-bis(trifluoromethyl)benzene, decafluoro-1,3-dimethylbenzene, and perfluoro-1,3-dimethylcyclohexane.Para-xylene at 350 deg C afforded 1,4-bis(difluoromethyl)tetrafluorobenzene, 1-difluoromethyl-4-trifluoromethyltetrafluorobenzene, decafluoro-1,4-dimethylbenzene (XIX), and perfluoro-1,4-dimethylcyclohexane (XVIII).Defluorination occurred to a significant extent on passage of the saturated cyclic fluorocarbons (I) and (XVIII) over the fully spent fluorinating agent (presumably caesium trifluorocobaltate) at ca. 400 deg C; the fluorocarbon arenes, (III) and (XIX) respectively, were obtained.