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2-(2-nitrophenyl)ethylsulfonyl chloride is an organic chemical compound with the molecular formula C8H8ClNO4S. It is a derivative of ethylsulfonyl chloride, featuring a 2-nitrophenyl group attached to the ethyl chain. 2-(2-nitrophenyl)ethylsulfonyl chloride is characterized by its yellowish color and is soluble in organic solvents. It is primarily used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly in the production of sulfonamide drugs. Due to its reactivity, it is essential to handle 2-(2-nitrophenyl)ethylsulfonyl chloride with care, as it can undergo nucleophilic substitution reactions with amines and other nucleophiles, leading to the formation of sulfonamide derivatives.

3192-07-2

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3192-07-2 Usage

Organosulfur compound

It is an organic compound that contains sulfur, which is a key element in its chemical properties and reactivity.

Chemical intermediate

It is frequently used as a starting material or intermediate in the production of various pharmaceuticals and agrochemicals, as well as in other industries.

Highly reactive nature

2-(2-nitrophenyl)ethylsulfonyl chloride is known for its high reactivity, making it a useful reagent in organic synthesis.

Introduction of sulfonyl groups

It is often used to introduce sulfonyl groups (-SO2-) onto other molecules, which can alter the properties and reactivity of those molecules.

Building block in synthesis

2-(2-nitrophenyl)ethylsulfonyl chloride serves as a valuable building block in the synthesis of a wide range of biologically active compounds.

Chemical research and development

Due to its reactivity and utility in introducing sulfonyl groups, it is a valuable tool in the field of chemical research and development.

Hazardous material

It is considered a hazardous material due to its potential for causing irritation and other health hazards.

Handling and storage precautions

2-(2-nitrophenyl)ethylsulfonyl chloride should be handled and stored with caution to minimize the risk of exposure and potential health hazards.

Check Digit Verification of cas no

The CAS Registry Mumber 3192-07-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,9 and 2 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3192-07:
(6*3)+(5*1)+(4*9)+(3*2)+(2*0)+(1*7)=72
72 % 10 = 2
So 3192-07-2 is a valid CAS Registry Number.

3192-07-2Relevant academic research and scientific papers

Nucleoside derivatives with photolabile protective groups

-

, (2008/06/13)

The invention relates to nucleo-side derivatives with photo-unstable protective groups of the general formula (I) in which R1 is H, NO2, CN, OCH3, halogen, alkyl or alkoxyalkyl with 1 to 4 C atoms, R2 is H, OCH3, R3 is H, F, Cl, Br, NO2 or an aliphatic ac

New photolabile protecting groups of the 2-(2- nitrophenyl)ethoxycarbonyl-and the 2-(2-nitrophenyl)ethylsulfonyl-type for the oligonucleotide synthesis

Buehler,Giegrich,Pfleiderer

, p. 1281 - 1283 (2007/10/03)

New photolabile blocking groups have been synthesized and introduced into the 5'-OH position of thymidine. The 5'-O-protected thymidines were irradiated at 365 nm under identical conditions and the half-lives and thymidine yields were determined to investigate the influence of different substituents in the two corresponding series.

New photolabile protecting groups in nucleoside and nucleotide chemistry - Synthesis, cleavage mechanisms and applications

Giegrich,Eisele-Buehler,Hermann,Kvasyuk,Charubala,Pfleiderer

, p. 1987 - 1996 (2007/10/03)

New photolabile protecting groups have been found in the 2-(2- nitrophenyl)ethoxycarbonyl and the 2-(2-nitrophenyl)ethylsulfonyl group, respectively. The influence of substituents at the phenyl ring as well as the side-chain has been investigated regarding the photolysis rates on irradiation at 365 mn. β-Branching in the side-chain leads to highly increased rates of photodeprotection. A new type of photocleavage mechanism consisting of a photoinduced β-elimination process is proposed.

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