319442-16-5 Usage
Description
Thieno[3,2-d]pyrimidine, 4-chloro-2-methyl-, also known as a member of the thienopyrimidine family, is a chemical compound with the molecular formula C8H6ClN3S. It features a thieno ring fused to a pyrimidine ring, with a chlorine atom and a methyl group attached at specific positions. This versatile compound is known for its potential applications in medicinal chemistry and drug discovery.
Uses
Used in Pharmaceutical Industry:
Thieno[3,2-d]pyrimidine, 4-chloro-2-methylis used as a building block for the synthesis of various drugs and bioactive molecules. Its unique structure and functional groups make it a valuable component in the development of new therapeutic agents.
Used in Medicinal Chemistry:
Thieno[3,2-d]pyrimidine, 4-chloro-2-methylis studied for its potential pharmacological properties, including anti-cancer and anti-inflammatory activities. Its ability to modulate biological pathways and target specific receptors makes it a promising candidate for the treatment of various diseases.
Used in Drug Discovery:
As a versatile compound, Thieno[3,2-d]pyrimidine, 4-chloro-2-methylplays a crucial role in drug discovery. Researchers utilize its chemical properties to design and optimize new drug candidates, aiming to improve their efficacy, selectivity, and safety profiles. Thieno[3,2-d]pyrimidine, 4-chloro-2-methylserves as a valuable tool in the ongoing quest to develop innovative therapeutics for unmet medical needs.
Check Digit Verification of cas no
The CAS Registry Mumber 319442-16-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,9,4,4 and 2 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 319442-16:
(8*3)+(7*1)+(6*9)+(5*4)+(4*4)+(3*2)+(2*1)+(1*6)=135
135 % 10 = 5
So 319442-16-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H5ClN2S/c1-4-9-5-2-3-11-6(5)7(8)10-4/h2-3H,1H3
319442-16-5Relevant articles and documents
Thienopyrimidine derivative as an active ingredient a plant disease control agent (by machine translation)
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Paragraph 0097; 0098; 0099, (2018/07/31)
[Problem] in plant disease resistance-inducing gene expression found thienopyrimidine derivative effect, utilizing the thienopyrimidine derivatives, injuries to plant disease organisms[Solution] some of the thienopyrimidine derivatives, such as gene expression in a plant disease-resistance gene to induce PR-a 1, therefore cruciferous vegetables against plant diseases caused by pathogenic bacillus anthracis, exhibiting excellent control effect was found. [Drawing] no (by machine translation)
Discovery of new hit-molecules targeting Plasmodium falciparum through a global SAR study of the 4-substituted-2-trichloromethylquinazoline antiplasmodial scaffold
Desroches, Justine,Kieffer, Charline,Primas, Nicolas,Hutter, Sébastien,Gellis, Armand,El-Kashef, Hussein,Rathelot, Pascal,Verhaeghe, Pierre,Azas, Nadine,Vanelle, Patrice
, p. 68 - 86 (2016/09/21)
From 4 antiplasmodial hit-molecules identified in 2-trichloromethylquinazoline series, we conducted a global Structure-Activity relationship (SAR) study involving 26 compounds and covering 5 molecular regions (I – V), aiming at defining the corresponding
THIENO[3,2-D]PYRIMIDINE-6-CARBOXAMIDES AND ANALOGUES AS SIRTUIN MODULATORS
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, (2014/09/29)
Provided herein are novel substituted thieno[3,2-d]pyrimidine-6-carboxamide sirtuin inhibitors and methods of use thereof. The sirtuin inhibitors may be used for inhibiting a sirtuin-mediated biological process, and, e.g. for treating and/or preventing diseases and disorders including, but not limited to cancer, neurodegenerative disease and inflammation. Also provided herein are pharmaceutical compositions comprising these sirtuin inhibitors and compositions comprising a sirtuin inhibitor in combination with another therapeutic agent.
