319493-99-7Relevant articles and documents
Stereocontrolled synthesis of multi-functionalized β-substituted α-amino acids: Nitrone cycloaddition approach
Tamura,Yoshida,Sugita,Mita,Uyama,Morita,Ishiguro,Kawasaki,Ishibashi,Sakamoto
, p. 1553 - 1556 (2007/10/03)
Syn- and anti-β-substituted α-amino acids 1 and 2 were synthesized by employing nitrone-cycloaddition. The stereochemistries required were controlled via a (Z)-nitrone-exo transition state for syn-amino acid 1 and via an (E)-nitrone-exo transition state for anti-amino acid 2, respectively.