31967-09-6

Basic information

• Product Name: 1-Amino-2-piperidone
• Synonyms: 1-Amino-2-piperidone;1-Aminopiperidine-2-one
• CAS NO: 31967-09-6
• Molecular Formula: C₅H₁₀N₂O
• Molecular Weight: 114.15
• Mol File: 31967-09-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 207.7 °C at 760 mmHg
• Flash Point: 79.4 °C
• Appearance: /
• Density: 1.123 g/cm³
• Vapor Pressure: 0.222mmHg at 25°C
• Refractive Index: 1.508
• Storage Temp.: 2-8°C(protect from light)
• PKA: 3.42±0.20(Predicted)
• CAS DataBase Reference: 1-Amino-2-piperidone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Amino-2-piperidone(31967-09-6)
• EPA Substance Registry System: 1-Amino-2-piperidone(31967-09-6)

Safety Data

• Hazardous Substances Data: 31967-09-6(Hazardous Substances Data)

Usage

General Description

1-Amino-2-piperidone, also known as 2-piperidinone, 1-amino-, is a chemical used for pharmaceutical and biochemical research. It is a member of the piperidinones family, featuring a six-membered ring structure with a ketone and an amino group. It can act as an intermediate in certain synthetic pathways due to its reactive functional groups. The chemical is whitish-yellow in color, with its solid form appearing like crystals or powder. It's important to note that as it is a laboratory reagent, it should be handled with care due to potential hazards and health risks.

InChI:InChI=1/C5H10N2O/c6-7-4-2-1-3-5(7)8/h1-4,6H2

Upstream product

• 5454-83-1 5-bromovaleric acid methyl ester 
• 3184-13-2 L-ornithine hydrochloride 
• 16682-12-5 D-ornithine hydrochloride 
• 1069-31-4 DL-ornithine hydrochloride 
• 475562-30-2 C₂₀H₃₆N₂O₇S₂ 
• 475562-31-3 C₁₇H₃₂N₂O₆ 

Downstream Products

• 1068968-89-7 2-phenyl-pyrimidine-5-carboxylic acid N'-(2-oxo-piperidin-1-yl)-amide 
• 100134-97-2 1-benzoylamino-piperidin-2-one 
• 100119-16-2 1-(4-chloro-benzylidenamino)-piperidin-2-one 

Relevant articles and documents

A convergent and flexible approach to hydroxylamines, hydrazines and related structures

Intermolecular xanthate transfer radical addition to protected allyl hydroxylamine or hydrazine provides a new, flexible, and convergent route to adducts which can be readily elaborated into complex aromatic or heterocyclic hydroxylamine or hydrazine derivatives.

Remedies for reperfusion injury containing integrin alphanubeta 3 antagonist

An objective of the present invention is to provide an agent that is clinically effective in the treatment or prevention of reperfusion injury. The agent for use in the treatment or prevention of reperfusion injury according to the present invention comprises an integrin αvβ3 antagonist, a pharmaceutically acceptable salt thereof, or a solvate thereof as active ingredient.

m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM

An object of the present invention is to provide m-substituted benzoic acid derivatives having integrin αvβ3 antagonistic activity. The derivatives according to the present invention are compounds represented by formula (I) or pharmaceutically acceptable salts or solvates thereof, which are useful for the treatment or prevention of cardiovascular diseases, angiogenesis-related diseases, cerebrovascular diseases, cancers and metastasis thereof, immunological diseases, osteopathy and other diseases: wherein A represents an optionally substituted heterocyclic group containing two nitrogen atoms, a bicylic group or the like; D represents a bond, >NR4, >CR5R6, O, S, or -NR4-CR5R6-; X represents CH or N; R7 and R8 represent hydroxyl, alkyl or the like; Q represents >C=O or the like; R9 represents hydrogen, alkyl or the like; J represents a bond or alkylene; R10 represents optionally substituted hydroxyl, amino or the like; R11 represents hydrogen, alkyl or the like; m is 0 to 5; n is 0 to 4; and p and q are each 0 to 3.