16682-12-5

Basic information

• Product Name: D-Ornithine monohydrochloride
• Synonyms: D-ORN, HCL;D-ORNITHINE HCL;D(-)-ORNITHINE HYDROCHLORIDE;D-ORNITHINE HYDROCHLORIDE;D(-)-ORNITHINE MONOHYDROCHLORIDE;D-ORNITHINE MONOHYDROCHLORIDE;D-ORNITHINE-OH HCL;D-ORTHININE MONOHYDROCHLORIDE
• CAS NO: 16682-12-5
• Molecular Formula: C₅H₁₂N₂O₂*ClH
• Molecular Weight: 168.62
• EINECS: 240-729-3
• Product Categories: Amino Acids Derivatives;AMINO ACIDS;Ornithine [Org];Amino Acids and Derivatives;Amino hydrochloride;Amino Acids & Derivatives, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Pyridines
• Mol File: 16682-12-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 239 °C (dec.)(lit.)
• Boiling Point: 308.7 °C at 760 mmHg
• Flash Point: 140.5 °C
• Appearance: White to off-white crystalline powder
• Density: 1.165g/cm3
• Vapor Pressure: 0.00015mmHg at 25°C
• Storage Temp.: Store at RT.
• Solubility: Water (Slightly)
• BRN: 4153339
• CAS DataBase Reference: D-Ornithine monohydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: D-Ornithine monohydrochloride(16682-12-5)
• EPA Substance Registry System: D-Ornithine monohydrochloride(16682-12-5)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• F: 3-10
• Hazardous Substances Data: 16682-12-5(Hazardous Substances Data)

Usage

Description

D-Ornithine monohydrochloride is the monohydrochloride form of D-Ornithine. D-ornithine is a non-proteinogenic amino acid involved in the urea cycle by the splitting off of urea from arginine. Ornithine supplementation can attenuate fatigue in increasing the efficiency of energy consumption and promoting the excretion of ammonia.

References

https://pubchem.ncbi.nlm.nih.gov/compound/D-ornithine https://en.wikipedia.org/wiki/Ornithine

Chemical Properties

White to off-white crystalline powder

Uses

The D-enatiomer and putative metabolite of the non-essential amino acid L-Orthinine. Stress response studies show intracerebroventricular D-Ornithine Hydrochloride weakly attenuated stress response in neonatal chick under acute stressful condition.

Biochem/physiol Actions

D-Ornithine cleave proteins at cysteine residues.

InChI:InChI=1/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/p+1/t4-/m1/s1

Upstream product

• 50995-48-7 methyl 2,5-dibromovalerate 
• 77300-45-9 2,5-Bis(methoxycarbonylamino)valeriansaeure-methylester 

Downstream Products

• 722499-65-2 (3R)-3-benzyloxycarbonylamino-2-piperidinone 
• 606943-98-0 (3R)-3-benzyloxycarbonylamino-1-diaminophosphinyl-2-piperidinone 
• 88763-76-2 (R)-(+)-3-Amino-2-piperidinon 
• 334618-23-4 3-(R)-aminopiperidine dihydrochloride 
• 309956-78-3 (R)-piperidin-3-ylcarbamic acid tert-butyl ester 
• 214852-34-3 Fmoc-Arg-(Boc)2-OH 
• 1892-22-4 3-aminopiperidin-2-one 
• 3304-51-6 N-carboxybenzyl-L-ornithine 
• 40216-82-8 methyl (S)-2,5-diaminopentanoate dihydrochloride 
• 209983-73-3 C₁₂H₁₆N₂O 

Relevant articles and documents

Highly enantioselective synthesis of non-natural aliphatic α-amino acids via asymmetric hydrogenation

By employing a rhodium-Duanphos complex as the catalyst, β-alkyl (Z)-N-acetyldehydroamino esters were smoothly hydrogenated in a highly efficient and enantioselective way. Excellent enantioselectivities together with excellent yields were achieved for a series of substrates. An efficient approach for the synthesis of the intermediate of the orally administered anti-diabetic drugs Alogliptin and Linagliptin in the DPP-4 inhibitor class was also developed.