31970-30-6

Basic information

• Product Name: 5-(pyridin-3-yl)pyridin-2-amine
• Synonyms: 5-(pyridin-3-yl)pyridin-2-amine;[3,3']bipyridinyl-6-ylamine;3,3'-bipyridin-6-aMine
• CAS NO: 31970-30-6
• Molecular Formula: C₁₀H₉N₃
• Molecular Weight: 171
• Mol File: 31970-30-6.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-(pyridin-3-yl)pyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(pyridin-3-yl)pyridin-2-amine(31970-30-6)
• EPA Substance Registry System: 5-(pyridin-3-yl)pyridin-2-amine(31970-30-6)

Safety Data

• Hazardous Substances Data: 31970-30-6(Hazardous Substances Data)

Usage

General Description

5-(pyridin-3-yl)pyridin-2-amine is a chemical compound notable for comprising two pyridine rings attached to an amine group. Pyridine is an aromatic heterocyclic compound, similar to benzene but with a nitrogen atom replacing one carbon. Consequently, the properties of 5-(pyridin-3-yl)pyridin-2-amine are largely influenced by these pyridine molecules and the amine group. This chemical is typically used for various forms of research, particularly in creating various chemical and pharmaceutical products. Its specific characteristics, such as reactivity, toxicity, and potential safety concerns, would depend on the context and conditions of its use.

Upstream product

• 33349-46-1 3-(3'-pyridinyl)pyridine N-oxide 
• 39856-50-3 5-bromo2-nitropyridine 
• 1072-97-5 5-bromo-2-pyridylamine 
• 1692-25-7 3-pyridylboronic acid 
• 827614-64-2 2-aminopyridine-5-boronic acid pinacol ester 
• 626-55-1 3-Bromopyridine 
• 20511-12-0 2-amino-5-iodopyridine 
• 1072-98-6 5-chloro-2-pyridylamine 

Relevant articles and documents

Mild, General, and Regioselective Synthesis of 2-Aminopyridines from Pyridine N -Oxides via N -(2-Pyridyl)pyridinium Salts

A synthesis of 2-aminopyridines from pyridine N-oxides via their corresponding N-(2-pyridyl)pyridinium salts has been demonstrated and investigated. The reaction sequence features a highly regioselective conversion of the N-oxide into its pyridinium salt

WNT PATHWAY MODULATORS

The present invention relates to dihydropyrazolo[l,5-a]pyrimidine compounds of formula I, defined herein, as WNT pathways modulators, processes for making them, and pharmaceutical compositions comprising them. Methods of treatment of conditions mediated by WNT pathway signalling including cancer, fibrosis, stem cell and diabetic retinopathy, rheumatoid arthritis, psoriasis and myocardial infarction, comprising the compounds of formula I are also provided.

Tetraphosphine/palladium-catalyzed Suzuki-Miyaura coupling of heteroaryl halides with 3-pyridine- and 3-thiopheneboronic acid: An efficient catalyst for the formation of biheteroaryls

An easily prepared tetraphosphine N,N,N′,N′- tetra(diphenylphosphinomethyl)-1,2-ethylenediamine (L1) associated with [Pd(η3-C3H5)Cl]2 affords an efficient catalyst for Suzuki-Miyaura coupling of 3-pyridineboronic acid with heteroaryl bromides. Reaction could be performed with as little as 0.02 mol% catalyst and a high turnover number of 2500 is obtained. A wide range of substrates is investigated with satisfactory yields, and good compatibility with aminogroup-substituted pyridines and unprotected indole is exhibited. This protocol can also be applied successfully to the reaction of heteroaryl bromides with 3-thiopheneboronic acid. This Pd-tetraphosphine catalyst efficiently restrains the poisoning effect from heteroaryls, and shows good stability and longevity. Copyright 2013 John Wiley & Sons, Ltd. An easily prepared tetraphosphine L1 was successfully used in Pd catalyzed Suzuki reaction of heteroaryl bromides with 3-pyridineboronic acid. A high turnover number of 2 500 was achieved and a wide range of heteroaryl halides including aminopyridines and indole was tolerated. With this protocol the coupling of 3-thiopheneboronic acid with heteroaryl bromides could also proceed in good yields. This catalyst system efficiently restrained poisoning effect from heteroaryls, and exhibited good stability and longevity. Copyright